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Genetics Of Autoimmunity In Type I Diabetes
Who can join
Ages 2 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria (Families): * Families where at least one first-degree family member has type 1 diabetes * The diabetic proband in the family was diagnosed before the age of 39 * Family members must be at least 2 years old to participate Exclusion Criteria (Families): * Families with no history of type 1 diabetes * Families with a history of diabetes that is not type 1 (LADA, MODY, type 2 etc.) Inclusion Criteria (Controls): * No family history of type 1 diabetes or other autoimmune conditions * Age 2 or older Exclusion Criteria (Controls): * Personal or family history of autoimmune disease
About the study
The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 diabetes. Scientists think that a person's own immune system, directed by genetic and environmental factors play a major role in its development. Participation involves a blood draw, a brief medical history questionnaire and measurements of height and weight. Some participants will be asked to return for annual follow-up visits for 10 years.
What is being tested
- Blood Collection (other)
Sponsor: Medical College of Wisconsin · Participants: 4,000 · Started: 2001-08
Contact the study team
- Martin Hessner, PhD · Phone: 414-955-4903
Official record on ClinicalTrials.gov — NCT03648918
Locations in the U.S.
| Wisconsin | Medical College of Wisconsin, Milwaukee |
Conditions
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.