Home › Chronic Pain › NCT03705598

Tai Chi Intervention for Geriatric Pain Syndrome

Who can join

Ages 65 and older · All sexes

Inclusion Criteria:

1. be 65 years or older
2. report chronic multisite (≥2 sites) musculoskeletal pain
3. have had 1 or more falls in the past year or current use of an assistive device (a cane or walker)
4. be able to walk 20 feet without help
5. be able to communicate in English

Exclusion Criteria:

1. actively engage in moderate to vigorous exercise for more than 40 min/week
2. practiced Tai Chi or other mind-body exercise within the past year, or practiced Tai Chi or other mind-body exercise regularly for at least 3 months within the past 5 years
3. have cognitive impairment consistent with dementia (Montreal Cognitive Assessment (MOCA) score \< 18 after corrections),
4. have a diagnosis of a disease/condition that would interfere with their study participation (e.g., rheumatoid arthritis, stroke, Parkinson's disease, degenerative neuromuscular disease, unstable cardiac disease, Alzheimer's disease or other dementia, terminal disease)

About the study

Accumulating evidence supports that more pain, whether measured by number of pain sites or pain severity, is associated with poorer cognitive function and mobility, and fall risk in older persons. Tai Chi which holistically integrates physical and cognitive functions offers the possibility not only of alleviating pain but also improving attention and mobility in the many older adults who have chronic multisite pain. This proposed full-size randomized controlled Tai Chi trial is a direct extension of the investigators' previous work examining chronic pain, attention demands, mobility and falls in the older population, and is built on the investigators' National Institute on Aging-supported Tai Chi feasibility and acceptability pilot studies among older adults with multisite pain and risk for falls. The goal of this single-blinded randomized controlled trial is to examine the effects of a 24-week Tai Chi intervention on chronic pain, cognition, mobility, fear of falling, and fall rate in older adults with multisite pain and at risk for falls. The results of this study will provide a foundation to establish the clinical significance of Tai Chi in the management of chronic multisite pain and to explore the mechanisms through which Tai Chi improves chronic pain symptoms and lowers fall rate in at-risk older adults.

What is being tested

• Light physical exercise (behavioral)
• Tai Chi (behavioral)

Sponsor: University of Massachusetts, Boston · Participants: 266 · Started: Oct 1, 2026

Contact the study team

• Tongjian You, PhD · Phone: 6172875934
• Mekhala Rao, MPH · Phone: 6172876297

Official record on ClinicalTrials.gov — NCT03705598

Locations in the U.S.

Conditions

• Chronic Pain

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.