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Chronic Pain clinical trials recruiting in the U.S.

178 studies for Chronic Pain are recruiting participants at sites across the United States.

Chronic pain lasts longer than three months or the time in which you should have healed. It is not always curable, but treatments can help.

Cities with the most studies

By state

Recently updated studies

Safety and Efficacy of Mesenchymal Stem Cells Associated With Chronic Pancreatitis Pain

RecruitingEarly phase 1
Ages 18 to 75 · All sexes · Updated Sep 30, 2026 · NCT06205342

Scrambler Therapy in Chronic Pancreatitis

Recruiting
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07174609

Chronic Postsurgical Pain

RecruitingObservational study
Ages 5 to 17 · All sexes · Updated Sep 25, 2026 · NCT05764681

Insula Neuromodulation for Chronic Neuropathic Pain

Recruiting
Ages 18 to 80 · All sexes · Updated Sep 25, 2026 · NCT05404581

Remote Monitoring Using a Digital Platform

Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07837102

Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06094257

Multisite Advancement of Research on Chronic Posttraumatic Headache

Recruiting
Ages 18 to 70 · All sexes · Updated Sep 22, 2026 · NCT05620719

Brief Mindfulness Intervention for Pain Before an In-clinic Orthopedic Procedure

Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06471075

Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial

Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06565416

ARPA-H Smart Band-Aid to Measure Chronic Pain in Women

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · Women · Updated Sep 14, 2026 · NCT06994988

Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis

Recruiting
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT04996628

QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT03434392

RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT01719055

Chronic Widespread Pain in HIV: Novel Mechanisms and Therapeutics

RecruitingHealthy volunteers welcome
Ages 19 to 65 · All sexes · Updated Sep 11, 2026 · NCT04787848

Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.

Recruiting
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06374537

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain

RecruitingPhase 2
Ages 40 and older · All sexes · Updated Sep 4, 2026 · NCT07641517

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07641504

Patient Retrospective Outcomes (PRO)

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT01550575

Post Market Evaluation of Real World Outcomes and Durability to Support Implantable Inceptivâ„¢ Spinal Cord Stimulation Therapy

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07507422

The Teaspoon Study - Telefitting Spinal Cord Stimulation for Pain

Recruiting
Ages 22 and older · All sexes · Updated Sep 3, 2026 · NCT05741788

Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

Recruiting
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07190807

NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow

RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Aug 28, 2026 · NCT06373978

Group-Based Psychological Treatments Over Video Conference for Older Veterans With Chronic Pain

Recruiting
Ages 60 to 95 · All sexes · Updated Aug 28, 2026 · NCT06004804

Group Music Therapy for Chronic Pain Management in Active Duty Service Members

RecruitingPhase 2
Ages 18 to 64 · All sexes · Updated Aug 27, 2026 · NCT07755540

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.