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Post-Traumatic Stress Disorder Focused Psychodynamic Psychotherapy

A Pilot Randomized Controlled Trial of Trauma-Focused Psychodynamic Psychotherapy (TFPP) at the VA in Veterans With PTSD

Who can join

Ages 18 to 70 · All sexes

Inclusion Criteria:

* Reporting moderate PTSD, as defined by a CAPS score of \>40
* Have at least one of the following history with CPT and/or PE:

  * offered and declined
  * dropped out of treatment
  * been determined unsuitable by their treatment team
  * received treatment but continue to experience symptoms meeting entrance criteria.
* Require stabilization on psychiatric medication for 2 month period prior to entry into study to avoid confounding treatments

Exclusion Criteria:

* Presence of SCID-5 assessed psychotic disorder, bipolar disorder, or substance use that would interfere with trial demands
* Severe suicidality that would require immediate crisis management
* Organic mental syndromes, delirium, or unstable medical conditions that would interfere with trial demands
* Inability to meet trial demands.

About the study

This is a randomized controlled trial of Trauma-Focused Psychodynamic Psychotherapy (TFPP) in comparison with TAU (at the VA) in a 2:1 ratio in 75 Veterans with PTSD who have not responded to standard treatment at the VA.

What is being tested

• TFPP (other)
• TAU (other)

Sponsor: Montefiore Medical Center · Participants: 75 · Started: Nov 2, 2018

Contact the study team

• Emily Villeveuve · Phone: (212) 686-7500
• Cory K Chen, Ph.D. · Phone: (212) 686-7500

Official record on ClinicalTrials.gov — NCT03755401

Locations in the U.S.

Conditions

• Post-Traumatic Stress Disorder

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.