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Post-Traumatic Stress Disorder clinical trials recruiting in the U.S.

245 studies for Post-Traumatic Stress Disorder are recruiting participants at sites across the United States.

 You can get Post-Traumatic Stress Disorder (PTSD) after experiencing a traumatic event. PTSD starts at different times for different people.

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Recently updated studies

Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease

RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT06952933

Written Exposure Therapy for Childbirth-related Post-Traumatic Stress

Recruiting
Ages 18 and older · Women · Updated Nov 13, 2026 · NCT07935070

Project Safe Guard-Trauma

Recruiting
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT06876740

Rehabilitation Through Virtual Immersion & Integrated Exposure for Mild Traumatic Brain Injury (ReVIVE for mTBI)

RecruitingPhase 1
Ages 18 to 55 · All sexes · Updated Nov 12, 2026 · NCT07890337

A Mechanistic Trial of the Neurobiology of Extinction Learning and Intraparietal Sulcus Stimulation

Recruiting
Ages 18 to 60 · All sexes · Updated Nov 12, 2026 · NCT06234969

Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD

Recruiting
Ages 30 to 55 · All sexes · Updated Nov 12, 2026 · NCT05380050

Psychotherapy Effects on Reward Processing in PTSD

Recruiting
Ages 18 to 65 · All sexes · Updated Nov 12, 2026 · NCT06096740

Post-Traumatic Stress Disorder Focused Psychodynamic Psychotherapy

Recruiting
Ages 18 to 70 · All sexes · Updated Nov 12, 2026 · NCT03755401

Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSD

RecruitingPhase 4
Ages 19 to 90 · All sexes · Updated Nov 9, 2026 · NCT07382596

NightWare and Cardiovascular Health in Women With PTSD

RecruitingHealthy volunteers welcome
Ages 22 to 40 · Women · Updated Nov 6, 2026 · NCT07021014

The Effects of Orexin Antagonism on Fear Extinction in PTSD

RecruitingPhase 4
Ages 18 to 75 · All sexes · Updated Nov 5, 2026 · NCT06788522

Restorative Early Sleep Treatment After the Emergency Department

Recruiting
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07121270

An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07836647

Open-Label Psilocybin Study in Transdiagnostic Population

RecruitingPhase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT06442423

Recovering Sleep After Trauma

Recruiting
Ages 18 to 65 · All sexes · Updated Oct 29, 2026 · NCT07196332

PTSD Screening in Pregnant Black Women

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT06522022

Randomized Trial of Tele Vs. Clinic TF-CBT in Puerto Rico

Recruiting
Ages 7 to 18 · All sexes · Updated Oct 26, 2026 · NCT06332209

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Oct 23, 2026 · NCT07226232

Exercise and Emotional Learning in Posttraumatic Stress Disorder

Recruiting
Ages 18 to 64 · All sexes · Updated Oct 21, 2026 · NCT06127342

Mindfulness-based Psilocybin Therapy for PTSD

RecruitingPhase 2
Ages 21 to 65 · All sexes · Updated Oct 19, 2026 · NCT07104916

OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit

Recruiting
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT05156112

Neuromodulation and Neurorehabilitation for mTBI

Recruiting
Ages 18 to 80 · All sexes · Updated Oct 16, 2026 · NCT03819608

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.