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Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

RecruitingPhase 4Healthy volunteers welcome

Who can join

Ages 60 and older · Women · Healthy volunteers welcome

Full eligibility criteria
Mayo Clinic Rochester-

Inclusion Criteria:

* Women who previously participated in this study
* Currently aged 60 years and older
* More than six months post chemotherapy or major surgery requiring general anesthesia
* Willing and able to sign informed consent

Exclusion Criteria:

* Not able to read and speak English
* In hospice
* Claustrophobic
* If undergoing Tau imaging, cannot have QT Prolongation

Mayo Clinic Jacksonville-

Inclusion Criteria:

* African American Women
* Currently aged 60 years and older
* More than six months post chemotherapy or major surgery requiring general anesthesia
* Willing and able to sign informed consent

Exclusion Criteria:

* Not able to read and speak English
* In hospice
* Claustrophobic
* If undergoing Tau imaging, cannot have QT Prolongation

About the study

The researchers are trying to determine whether ovarian hormones are associated with aging processes and with the risk of developing Alzheimer's disease in women.

What is being tested

Sponsor: Mayo Clinic · Participants: 614 · Started: Jun 27, 2019

Contact the study team

Official record on ClinicalTrials.gov — NCT03821857

Locations in the U.S.

FloridaMayo Clinic, Jacksonville

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.