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Alzheimer's Disease clinical trials recruiting in the U.S.
243 studies for Alzheimer's Disease are recruiting participants at sites across the United States.
Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.
Cities with the most studies
- Orlando, FL29 studies
- Boston, MA28 studies
- St. Louis, MO22 studies
- Miami, FL21 studies
- New York City, NY21 studies
- Tampa, FL20 studies
- Atlanta, GA19 studies
- The Villages, FL18 studies
- Phoenix, AZ15 studies
- West Palm Beach, FL15 studies
- Los Angeles, CA14 studies
- Philadelphia, PA14 studies
- Indianapolis, IN14 studies
- Newton, MA13 studies
- Chicago, IL12 studies
- Irvine, CA12 studies
- Deltona, FL12 studies
- Dallas, TX12 studies
- San Diego, CA11 studies
- Houston, TX11 studies
- Port Saint Lucie, FL11 studies
- Baltimore, MD11 studies
- Seattle, WA10 studies
- Farmington Hills, MI10 studies
- Long Beach, CA10 studies
- Nashville, TN10 studies
- Austin, TX10 studies
- Pittsburgh, PA10 studies
- Anaheim, CA9 studies
- Cape Coral, FL9 studies
- Providence, RI9 studies
- Queens, NY9 studies
- Portland, OR9 studies
- Boca Raton, FL8 studies
- Jacksonville, FL8 studies
- New Haven, CT8 studies
- San Antonio, TX8 studies
- Melbourne, FL8 studies
- Hollywood, FL8 studies
- San Francisco, CA8 studies
By state
- Alabama8 studies
- Arizona23 studies
- California50 studies
- Colorado14 studies
- Connecticut12 studies
- District of Columbia5 studies
- Florida54 studies
- Georgia29 studies
- Hawaii3 studies
- Illinois20 studies
- Indiana16 studies
- Kansas5 studies
- Kentucky3 studies
- Louisiana8 studies
- Maryland14 studies
- Massachusetts46 studies
- Michigan17 studies
- Minnesota8 studies
- Mississippi5 studies
- Missouri26 studies
- Nevada7 studies
- New Jersey25 studies
- New York38 studies
- North Carolina19 studies
- Ohio17 studies
- Oklahoma6 studies
- Oregon10 studies
- Pennsylvania23 studies
- Rhode Island9 studies
- South Carolina4 studies
- Tennessee16 studies
- Texas38 studies
- Utah6 studies
- Virginia13 studies
- Washington17 studies
- Wisconsin7 studies
Recently updated studies
PET Imaging in the Baltimore Longitudinal Study of Aging (BLSA)
RecruitingObservational studyHealthy volunteers welcome
Ages 55 to 110 · All sexes · Updated Nov 13, 2026 · NCT07099053Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
RecruitingHealthy volunteers welcome
Ages 18 to 89 · All sexes · Updated Nov 13, 2026 · NCT04800588Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin
RecruitingPhase 2Healthy volunteers welcome
Ages 65 to 120 · All sexes · Updated Nov 13, 2026 · NCT07721467Adaptango Performance PRocess for Older Adults Community reHabilitation
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07824128A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
RecruitingPhase 2
Ages 55 to 90 · All sexes · Updated Nov 12, 2026 · NCT06887192A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT05231785A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Nov 12, 2026 · NCT06937229Make Better Choices 2 for Rural Appalachians
RecruitingHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Nov 10, 2026 · NCT04309461Tennessee Alzheimer's Project
RecruitingObservational studyHealthy volunteers welcome
Ages 60 and older · All sexes · Updated Nov 10, 2026 · NCT05372172Testing the Effects of a Text Message Caregiver Support Intervention for Latinos
RecruitingHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Nov 9, 2026 · NCT06728436CMN LIFU for Enhanced Amyloid Reduction (CLEART Study)
Recruiting
Ages 65 and older · All sexes · Updated Nov 9, 2026 · NCT07866768GAPcareAD: A Brief Emergency Department Intervention to Address Post-Fall Care Needs of Persons Living With Dementia and Care Partners
Recruiting
Ages 65 and older · All sexes · Updated Nov 9, 2026 · NCT07563270A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Nov 6, 2026 · NCT07011732HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms
RecruitingHealthy volunteers welcome
Ages 60 to 100 · All sexes · Updated Nov 6, 2026 · NCT06930560A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Nov 6, 2026 · NCT07688213A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
RecruitingPhase 3
Ages 55 to 80 · All sexes · Updated Nov 6, 2026 · NCT07717411Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease
RecruitingPhase 1/2
Ages 50 to 86 · All sexes · Updated Nov 6, 2026 · NCT07651319Study to Test Effects and Safety of RO7568282 in Early Symptomatic Alzheimer's Disease
RecruitingPhase 2
Ages 50 to 90 · All sexes · Updated Nov 6, 2026 · NCT07781657Flutemetamol F 18 Injection Formulation Comparison
RecruitingPhase 2
Ages 50 to 110 · All sexes · Updated Nov 5, 2026 · NCT07873463A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Nov 5, 2026 · NCT07787169A Study of LY3439539 in Participants With Alzheimer's Disease
RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Nov 4, 2026 · NCT07598370A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Nov 4, 2026 · NCT07589595A Real-World Comparative Study of Donanemab (LY3002813) Plus Usual Care Versus Usual Care Alone in US Participants With Early Symptomatic Alzheimer's Disease
RecruitingObservational study
Ages 60 and older · All sexes · Updated Nov 3, 2026 · NCT06566170A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Nov 3, 2026 · NCT07011745A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
RecruitingPhase 2
Ages 55 and older · All sexes · Updated Nov 3, 2026 · NCT06540833From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.