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Alzheimer's Disease clinical trials recruiting in the U.S.

237 studies for Alzheimer's Disease are recruiting participants at sites across the United States.

Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.

Cities with the most studies

By state

Recently updated studies

Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging

RecruitingObservational studyHealthy volunteers welcome
Ages 55 to 110 · All sexes · Updated Sep 28, 2026 · NCT07099053

Randomized Study to Evaluate the Effect of Obicetrapib in Participants With Preclinical Alzheimer's Disease

RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 28, 2026 · NCT07794670

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Sep 28, 2026 · NCT06937229

Dominantly Inherited Alzheimer Network (DIAN)

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT00869817

A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

RecruitingPhase 4
Ages 50 and older · All sexes · Updated Sep 25, 2026 · NCT07633470

A Study of LY3439539 in Participants With Alzheimer's Disease

RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Sep 24, 2026 · NCT07598370

Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

RecruitingHealthy volunteers welcome
Ages 50 to 100 · All sexes · Updated Sep 23, 2026 · NCT06094192

Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease

RecruitingPhase 1/2
Ages 50 to 86 · All sexes · Updated Sep 23, 2026 · NCT07651319

Combating Alzheimer's Through Sleep and Exercise

RecruitingHealthy volunteers welcome
Ages 55 to 80 · All sexes · Updated Sep 23, 2026 · NCT04855630

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07589595

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Sep 22, 2026 · NCT06585787

Predicting Pre-dementia

RecruitingObservational studyHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Sep 22, 2026 · NCT07516119

A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease

RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07688213

Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons

Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05048966

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

RecruitingPhase 3
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352

Music for Pain and Dementia

Recruiting
Ages 50 to 80 · All sexes · Updated Sep 21, 2026 · NCT07602283

Microbiome in Aging of Gut and Brain

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07799402

Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

RecruitingPhase 2
Ages 55 to 80 · All sexes · Updated Sep 21, 2026 · NCT06847321

The Gut - PRO Study

RecruitingPhase 1Healthy volunteers welcome
Ages 60 and older · All sexes · Updated Sep 21, 2026 · NCT07413744

PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620

RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05456503

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Sep 18, 2026 · NCT04396873

Pulsed Electromagnetic Field Treatment With Dementia Patients

Recruiting
Ages 50 to 100 · All sexes · Updated Sep 17, 2026 · NCT06862557

Pulsed Electromagnetic Field Treatment In Patients With Alzheimer's Disease

Recruiting
Ages 50 to 100 · All sexes · Updated Sep 17, 2026 · NCT05295615

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.