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Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their Caregivers

Dyadic Behavioral Interventions to Manage Physical Performance, Symptoms and Quality of Life for Patient Undergoing Radiotherapy and Their Family Caregivers

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* PATIENT ONLY: Diagnosed with stage I-IV non-small cell lung cancer (NSCLC) or esophageal cancer and going to receive at least 3 weeks of thoracic radiotherapy (RT)
* PATIENT ONLY: Eastern Cooperative Oncology Group (ECOG) performance status of ≤ 2
* PATIENT ONLY: Able to read, write and speak English
* PATIENT ONLY: Able to provide informed consent
* PATIENT ONLY: Having a family caregiver (e.g., spouse, sibling, adult child) who assists the patient during the cancer treatment (e.g., emotional support, transportation, meal preparation, care coordination, etc) per patient self-report. Note, patients must identify a family caregiver; however, the participation of the family caregiver is optional. For caregivers to be eligible, they must be at least 18 years old; able to read, write and speak English; and able to provide informed consent. Family caregivers may consent to participate in the intervention and caregiver assessments or only the assessments based on their preference.

Exclusion Criteria:

* PATIENT ONLY: Who have regularly (self-defined) participated in a mind-body practice in the year prior to diagnosis
* PATIENT ONLY: Patients who metastatic disease involving the central nervous system

About the study

This trial studies how well dyadic yoga intervention works in improving physical performance and quality of life in patients with stage I-IV non-small cell lung or esophageal cancer undergoing radiotherapy and their caregivers. Dyadic yoga intervention may help to improve physical function, fatigue, sleep difficulties, depressive symptoms, and overall quality of life for patients with non-small cell lung cancer and/or their caregivers.

What is being tested

• Educational Intervention (other)
• Quality-of-Life Assessment (other)
• Questionnaire Administration (other)
• Yoga (procedure)

Sponsor: M.D. Anderson Cancer Center · Participants: 400 · Started: Dec 20, 2018

Contact the study team

• Kathrin Milbury · Phone: 713-745-2868

Official record on ClinicalTrials.gov — NCT03948100

Locations in the U.S.

Conditions

• Esophageal Cancer
• Non-Small Cell Lung Cancer
• Lung Cancer

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.