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SV2 PET Imaging With [11C]APP311

RecruitingObservational studyHealthy volunteers welcome

Synaptic Density in Psychiatric Disorders Using SV2A Receptor PET Imaging With [11C]APP311

Who can join

Ages 18 to 85 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Willing and able to give voluntary written informed consent
* Male and Female subjects, age 18 to 65 years, inclusive

Exclusion Criteria:

* MRI metal exclusions and claustrophobia.
* Education completed is less than 12 years

About the study

The aim of this study is to evaluate a new SV2A tracer, \[11C\]APP311, in healthy aging and neuropsychiatric disorders including psychotic disorders and cannabis use disorders.

What is being tested

Sponsor: Yale University · Participants: 250 · Started: Dec 1, 2017

Contact the study team

Official record on ClinicalTrials.gov — NCT03995121

Locations in the U.S.

ConnecticutConneticut Mental Health Center, New Haven

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.