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Schizophrenia clinical trials recruiting in the U.S.
105 studies for Schizophrenia are recruiting participants at sites across the United States.
Schizophrenia is a serious brain illness that can include hearing voices that aren't there and thinking others are trying to hurt them.
Cities with the most studies
- Atlanta, GA21 studies
- Chicago, IL20 studies
- Little Rock, AR18 studies
- San Diego, CA15 studies
- Houston, TX14 studies
- Boston, MA14 studies
- Hollywood, FL14 studies
- Hialeah, FL13 studies
- Austin, TX12 studies
- Garden Grove, CA12 studies
- New York City, NY12 studies
- Miami, FL10 studies
- Germantown, MD10 studies
- Richardson, TX9 studies
- Camden, NJ9 studies
- Cincinnati, OH8 studies
- Philadelphia, PA8 studies
- Anaheim, CA8 studies
- Cambridge, MA8 studies
- Springdale, AR8 studies
- Inglewood, CA8 studies
- Los Angeles, CA8 studies
- St. Louis, MO8 studies
- Grand Prairie, TX8 studies
- Johns Creek, GA8 studies
- Dallas, TX7 studies
- Las Vegas, NV7 studies
- Staten Island, NY7 studies
- Queens, NY7 studies
- Orange, CA7 studies
- El Cajon, CA7 studies
- Torrance, CA7 studies
- Pittsburgh, PA7 studies
- Nashville, TN6 studies
- Richmond, VA6 studies
- Chino, CA6 studies
- Orlando, FL6 studies
- Oceanside, CA6 studies
- Downey, CA6 studies
- Riverside, CA6 studies
By state
- Alabama5 studies
- Arizona4 studies
- Arkansas21 studies
- California45 studies
- Connecticut9 studies
- Florida25 studies
- Georgia28 studies
- Illinois25 studies
- Maryland18 studies
- Massachusetts23 studies
- Michigan4 studies
- Minnesota6 studies
- Mississippi4 studies
- Missouri11 studies
- Nebraska6 studies
- Nevada7 studies
- New Jersey13 studies
- New York22 studies
- North Carolina4 studies
- Ohio16 studies
- Oklahoma4 studies
- Pennsylvania15 studies
- Tennessee6 studies
- Texas33 studies
- Virginia6 studies
- Washington8 studies
Recently updated studies
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)
RecruitingPhase 3
Ages 13 to 17 · All sexes · Updated Nov 12, 2026 · NCT07288567A Study to Evaluate the Effect of KarXT on Urological Safety
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Nov 10, 2026 · NCT07221877Confirmatory Trial of Gamma Neurofeedback to Improve Working Memory in Schizophrenia
RecruitingPhase 2
Ages 18 to 55 · All sexes · Updated Nov 10, 2026 · NCT07592169A Study to Assess the Safety, Tolerability and Pharmacokinetics of XEP527 in Patients With Stable Schizophrenia
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Nov 9, 2026 · NCT07908680Cognitive Neurocomputational Task Reliability & Clinical Applications Consortium (CNTRACS): Study 1
RecruitingHealthy volunteers welcome
Ages 18 to 59 · All sexes · Updated Nov 9, 2026 · NCT07853807Cognitive Neurocomputational Task Reliability and Clinical Applications Consortium: Study 3
RecruitingHealthy volunteers welcome
Ages 18 to 59 · All sexes · Updated Nov 9, 2026 · NCT07900893A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents
RecruitingPhase 3
Ages 5 to 17 · All sexes · Updated Nov 6, 2026 · NCT07424404REACH Study (Recovery Environments: Assessing Cognitive & Brain Health in Community Mental Health)
Recruiting
Ages 18 to 50 · All sexes · Updated Nov 4, 2026 · NCT07006935Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder
RecruitingPhase 3
Ages 5 to 17 · All sexes · Updated Nov 3, 2026 · NCT06229210A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia
RecruitingPhase 1
Ages 18 to 60 · All sexes · Updated Nov 3, 2026 · NCT07615426Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07379827Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Oct 30, 2026 · NCT07686263Study to Evaluate the Safety and Efficacy of Ublituximab in Participants With Schizophrenia
RecruitingPhase 2
Ages 18 to 60 · All sexes · Updated Oct 30, 2026 · NCT07680946Impact of Cerebellar TMS on Brain and Cognitive Functions in Schizophrenia: a Pilot Study
Recruiting
Ages 18 to 60 · All sexes · Updated Oct 28, 2026 · NCT05389787The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia
RecruitingHealthy volunteers welcome
Ages 18 to 45 · All sexes · Updated Oct 20, 2026 · NCT06386588A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Oct 15, 2026 · NCT07459647iTBS to Enhance Social Cognition in People With Psychosis
Recruiting
Ages 18 to 39 · All sexes · Updated Oct 8, 2026 · NCT06118268A Study of Brenipatide in Adult Participants With Schizophrenia
RecruitingPhase 2
Ages 18 to 55 · All sexes · Updated Oct 7, 2026 · NCT07410507Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05491538Safety and Tolerability of Open-Labeled Iloperidone in Adolescents
RecruitingPhase 4
Ages 12 to 17 · All sexes · Updated Oct 1, 2026 · NCT05648591Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls
RecruitingHealthy volunteers welcome
Ages 18 to 50 · All sexes · Updated Oct 1, 2026 · NCT07680114Volatility in Paranoia (VIP) Trial: An RCT of Changes in Volatility With Psychotherapy
Recruiting
Ages 18 to 65 · All sexes · Updated Sep 30, 2026 · NCT06835556Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07101094Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 25, 2026 · NCT07227818NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 25, 2026 · NCT07105098From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.