Behavioral and Neural Representations of Subjective Effort Cost
Who can join
Ages 18 to 35 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Right-handed * Age between 18 and 35 years old - Male or female * Any ethnicity Exclusion Criteria: Individuals with a history of any of the following will be excluded from the study: * Neurological problems such as stroke, head injury, epilepsy, seizures, brain tumors, brain surgery, Parkinson's Disease (self- report) * Diagnosed history of severe psychiatric disease such as depression, schizophrenia (self-report) * Metal in the head or eyes * If they are pregnant or suspect that you may be pregnant * If they experience discomfort from the MRI scan, such as severe claustrophobia or excessive heating of tattoos
About the study
The goal of this proposal is to understand the common and distinct behavioral and neural representations of subjective effort valuation, and how these representations are influenced by fatigue and changes in motivation. It is hypothesized that the brain will use overlapping and distinct neural circuits to represent cognitive and physical effort value, and that fatigue and enhanced motivation will influence the subjective value of effort.
What is being tested
- Cognitive Fatigue (behavioral)
- Physical Fatigue (behavioral)
- Rewarding Stimuli (behavioral)
Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc. · Participants: 185 · Started: Aug 1, 2018
Contact the study team
- Anthony Gonzalez · Phone: 443-923-2716
Official record on ClinicalTrials.gov — NCT04041154
Locations in the U.S.
| Maryland | Kennedy Krieger Institute, Baltimore |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.