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Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias

RecruitingObservational study

Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias Symptomatic Using Novel CARTO Technologies: REAL Registry

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
REAL AF Cohort

Inclusion Criteria:

* Symptomatic PAF (AF episode terminate spontaneously within 7 days) or PsAF (AF sustained beyond 7 days, but less than 365 days) subjects who, in the opinion of the investigator, are candidates for catheter ablation.
* \>18 years of age.
* Will be treated with Biosense Webster Inc. ablation technologies
* All AF ablations performed with BWI catheters are included. This includes repeat ablations where the index procedure was performed with a non-BWI catheter.
* Able and willing to participate in baseline and follow up evaluations
* Willing and able to provide informed consent, if applicable.

Exclusion Criteria:

* Enrolled in an investigational drug or device clinical trial, or any trial that dictates the treatment plan
* Long-standing persistent AF (AF greater than one year)
* In the opinion of the investigator, any known contraindication to an ablation procedure

CORE VA Cohort

Inclusion Criteria:

* Documented ventricular arrhythmia appropriate for catheter ablation.
* \>18 years of age.
* Will be treated with Biosense Webster Inc. ablation technologies
* Able and willing to participate in baseline and follow up evaluations
* Willing and able to provide informed consent, if applicable.

Exclusion Criteria:

* Enrolled in an investigational drug or device clinical trial, or any trial that dictates the treatment plan.
* In the opinion of the investigator, any known contraindication to an ablation procedure.

About the study

The primary purpose of this Registry is to assess procedural safety and long-term effectiveness of catheter ablations in the treatment of subjects with PAF, PsAF, and VA. The Registry will utilize real world clinical data obtained from the use of commercially available CARTO™ technologies under the authority of a health care practitioner within a legitimate practitioner-subject relationship. Data from the registry will be used to assess clinical outcomes, including procedural efficiency, safety, and long-term effectiveness of catheter ablation with novel technologies for arrhythmia patients.

What is being tested

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC · Participants: 20,000 · Started: Jan 1, 2018

Contact the study team

Official record on ClinicalTrials.gov — NCT04088071

Locations in the U.S.

AlabamaGrandview Medical Center, Birmingham
University of Alabama at Birmingham, Birmingham
Cardiology Associates of Mobile, Mobile
ArizonaValley Heart Rhythm Specialists, Chandler
Pima Heart and Vascular, Tucson
ArkansasArrhythmia Research Group, Jonesboro
CaliforniaKeck School of Medicine, Los Angeles
Community Memorial Hospital, Ventura
ColoradoThe Medical Center of Aurora, Aurora
Colorado Heart and Vascular, Golden
South Denver Cardiology, Littleton
FloridaAscension St. Vincent's, Jacksonville
HCA Florida Mercy Hospital, Miami
Naples Community Hospital, Naples
Ascension Sacred Heart, Pensacola
Sarasota Memorial Hospital, Sarasota
Baycare Health Tampa, Tampa
Baycare Health System, Winterhaven
GeorgiaPiedmont Healthcare, Atlanta
Memorial Health University Medical Center, Savannah
IllinoisNorthshore University Health System, Evanston
Midwest Cardiovascular Institute, Naperville
Prairie Education and Research, Springfield
IndianaAscension St. Vincent's Hospital, Indianapolis
IowaUniversity of Iowa, Iowa City
KentuckyNorton Heart Specialists, Louisville
Baptist Health Louisville, Saint Matthews
MaineMaine Medical Center, Portland
MarylandCapitol CArdiology, Lanham
MassachusettsBrigham and Women's Hospital, Boston
MichiganHenry Ford Health, Detroit
Sparrow Clinical Research, Lansing
William Beaumont Hospital, Royal Oak
Michigan Heart, Ypsilanti
MississippiMississippi Baptist Medical Center, Jackson
MissouriUniversity of Missouri, Columbia
CoxHealth, Springfield
New JerseyCardiovascular Associates of the Delaware Valley, Haddon Heights
New MexicoLovelace Health System, Albuquerque
New YorkColumbia University Medical Center / NewYork-Presbyterian Hospital (CUMC/NYPH), New York
Nuvance Health, Poughkeepsie
Crouse Health System and Crouse Medical Practice, Syracuse
North CarolinaMission Hospital, Asheville
Novant Health Forsyth Medical Center, Winston-Salem
OhioThe Christ Hospital, Cincinnati
University of Cincinnati, Cincinnati
Mount Carmel Columbus Cardiology Consultants, Columbus
OklahomaOklahoma Heart Hospital, Oklahoma City
PennsylvaniaLancaster General Hospital, Lancaster
University of Pennsylvania, Penn Presbyterian Medical Center, Philadelphia
Allegheny Health Network, Pittsburgh
WellSpan Health, York
South CarolinaUpstate Cardiology, Greenville
TennesseeJackson-Madison County General Hospital, Jackson
TexasTexas Cardiac Arrhythmia Foundation, Austin
Baylor Scott & White Research Institute, Dallas
Medical City Dallas Hospital, Dallas
UtahSt. Mark's Hospital, Salt Lake City
VirginiaCentra Health, Inc. dba Stroobants Cardiovascular Center, Lynchburg
Bon Secours St. Marys, Midlothian
CJW Medical Center, Richmond
Valley Health, Winchester
WashingtonUniversity of Washington-Seattle, Seattle
MultiCare Institute for Research & Innovation, Tacoma
WisconsinMercyHealth, Janesville
University of Wisconsin, Madison

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.