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Atrial Fibrillation clinical trials recruiting in the U.S.
108 studies for Atrial Fibrillation are recruiting participants at sites across the United States.
Atrial fibrillation (AF or AFib) is the most common type of arrhythmia (irregular heartbeat). Read about symptoms and treatment.
Cities with the most studies
- New York City, NY21 studies
- Boston, MA17 studies
- Cleveland, OH17 studies
- Atlanta, GA16 studies
- Philadelphia, PA12 studies
- Chicago, IL12 studies
- Jonesboro, AR12 studies
- Ann Arbor, MI11 studies
- Cincinnati, OH10 studies
- Columbus, OH10 studies
- Pittsburgh, PA10 studies
- Queens, NY9 studies
- Indianapolis, IN9 studies
- Austin, TX9 studies
- Houston, TX9 studies
- Los Angeles, CA9 studies
- St. Louis, MO9 studies
- Dallas, TX9 studies
- New Orleans, LA9 studies
- Orlando, FL9 studies
- Evanston, IL8 studies
- Washington, DC8 studies
- Aurora, CO8 studies
- Overland Park, KS8 studies
- Durham, NC7 studies
- Salt Lake City, UT7 studies
- Miami, FL7 studies
- Oklahoma City, OK7 studies
- San Francisco, CA7 studies
- Jacksonville, FL7 studies
- Baltimore, MD7 studies
- San Diego, CA7 studies
- Sarasota, FL7 studies
- Huntington Beach, CA7 studies
- Ventura, CA7 studies
- Tampa, FL7 studies
- The Bronx, NY7 studies
- Birmingham, AL7 studies
- Mountain View, CA6 studies
- Charlottesville, VA6 studies
By state
- Alabama11 studies
- Arizona10 studies
- Arkansas14 studies
- California30 studies
- Colorado12 studies
- Connecticut5 studies
- District of Columbia5 studies
- Florida22 studies
- Georgia17 studies
- Illinois22 studies
- Indiana12 studies
- Iowa7 studies
- Kansas11 studies
- Kentucky11 studies
- Louisiana13 studies
- Maine5 studies
- Maryland11 studies
- Massachusetts19 studies
- Michigan20 studies
- Minnesota9 studies
- Missouri12 studies
- Nebraska3 studies
- New Jersey10 studies
- New Mexico3 studies
- New York33 studies
- North Carolina15 studies
- Ohio30 studies
- Oklahoma8 studies
- Oregon4 studies
- Pennsylvania19 studies
- South Carolina8 studies
- South Dakota3 studies
- Tennessee12 studies
- Texas24 studies
- Utah10 studies
- Virginia15 studies
- Washington10 studies
- West Virginia3 studies
- Wisconsin8 studies
Recently updated studies
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
RecruitingPhase 3
Ages 22 to 85 · All sexes · Updated Sep 28, 2026 · NCT05836987Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07626411Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07175428A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07217067Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06376916A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation
Recruiting
Ages 18 to 80 · All sexes · Updated Sep 25, 2026 · NCT07527299Optimal Anti-Thrombotic Management Following Percutaneous Left Atrial Appendage Occlusion
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07840365Evaluation of the FARAFLEX Mapping and Pulsed Field Ablation System in Subjects With Atrial Fibrillation
Recruiting
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07575269Comparing the Safety and Efficacy of Apixaban and Rivaroxaban
RecruitingPhase 4
Ages 22 and older · All sexes · Updated Sep 23, 2026 · NCT06953726ReVeRA-301: Etripamil in Atrial Fibrillation Phase 3
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06716021Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT04088071PULSED AF Post-Approval Study
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06578104The Fourth Left Atrial Appendage Occlusion Study
Recruiting
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05963698Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07430956A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation
Recruiting
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07523750Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT00921986Post-ablation Alcohol Impacts Arrhythmia Recurrence, Quality of Life and Cognition in AF
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 14, 2026 · NCT05510167Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07436299CellFX® Nanosecond Pulsed Field Ablation (nsPFA)™ Cardiac Surgery Clamp System to Treat Atrial Fibrillation
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 9, 2026 · NCT06959121High-resolution MRI of Atrial Fibrillation Patients Prior to Focal Impulse and Rotor Modulation (FIRM) Ablation
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT03444337A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 9, 2026 · NCT07625215Evaluation of 4D Intracardiac Echocardiography (ICE) During Structural Heart and Electrophysiology Procedures
Recruiting
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07806890Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 8, 2026 · NCT07122947A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System
Recruiting
Ages 22 and older · All sexes · Updated Aug 31, 2026 · NCT07227532BOdygUardian MOnitoriNg for ReCurrencE of AF
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07671677From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.