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Atrial Fibrillation clinical trials recruiting in the U.S.
107 studies for Atrial Fibrillation are recruiting participants at sites across the United States.
Atrial fibrillation (AF or AFib) is the most common type of arrhythmia (irregular heartbeat). Read about symptoms and treatment.
Cities with the most studies
- Boston, MA19 studies
- New York City, NY19 studies
- Atlanta, GA17 studies
- Cleveland, OH17 studies
- Jonesboro, AR13 studies
- Pittsburgh, PA12 studies
- Philadelphia, PA12 studies
- Ann Arbor, MI12 studies
- Chicago, IL12 studies
- Orlando, FL11 studies
- Cincinnati, OH10 studies
- Austin, TX10 studies
- Columbus, OH10 studies
- Indianapolis, IN10 studies
- St. Louis, MO10 studies
- Houston, TX10 studies
- Dallas, TX9 studies
- Los Angeles, CA9 studies
- Jacksonville, FL9 studies
- Miami, FL8 studies
- Aurora, CO8 studies
- Evanston, IL8 studies
- Queens, NY8 studies
- New Orleans, LA8 studies
- Washington, DC7 studies
- Detroit, MI7 studies
- Oklahoma City, OK7 studies
- Ventura, CA7 studies
- Louisville, KY7 studies
- Birmingham, AL7 studies
- Salt Lake City, UT7 studies
- Huntington Beach, CA7 studies
- Durham, NC7 studies
- Baltimore, MD7 studies
- The Bronx, NY7 studies
- San Francisco, CA7 studies
- San Diego, CA7 studies
- Sarasota, FL6 studies
- Mobile, AL6 studies
- Tampa, FL6 studies
By state
- Alabama12 studies
- Arizona12 studies
- Arkansas16 studies
- California30 studies
- Colorado12 studies
- Connecticut5 studies
- District of Columbia4 studies
- Florida22 studies
- Georgia18 studies
- Idaho3 studies
- Illinois22 studies
- Indiana12 studies
- Iowa8 studies
- Kansas8 studies
- Kentucky13 studies
- Louisiana12 studies
- Maine5 studies
- Maryland12 studies
- Massachusetts22 studies
- Michigan22 studies
- Minnesota9 studies
- Mississippi3 studies
- Missouri12 studies
- Nebraska3 studies
- New Jersey12 studies
- New Mexico3 studies
- New York31 studies
- North Carolina16 studies
- Ohio30 studies
- Oklahoma8 studies
- Oregon4 studies
- Pennsylvania22 studies
- South Carolina8 studies
- South Dakota4 studies
- Tennessee13 studies
- Texas25 studies
- Utah11 studies
- Virginia15 studies
- Washington11 studies
- West Virginia3 studies
- Wisconsin8 studies
Recently updated studies
Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial Fibrillation
Recruiting
Ages 40 and older · All sexes · Updated Nov 13, 2026 · NCT06938412Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Nov 13, 2026 · NCT06844227ReVeRA-301: Etripamil in Atrial Fibrillation Phase 3
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06716021PULSED AF Post-Approval Study
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06578104Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07430956Intracardiac Echocardiography Guided Watchman Device Implant
Recruiting
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT06007872Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07175428Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07626411A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System
Recruiting
Ages 22 and older · All sexes · Updated Nov 4, 2026 · NCT07227532A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation
Recruiting
Ages 18 to 80 · All sexes · Updated Nov 3, 2026 · NCT07523750The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
RecruitingPhase 3
Ages 22 to 85 · All sexes · Updated Nov 3, 2026 · NCT05836987A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation
Recruiting
Ages 18 to 80 · All sexes · Updated Nov 3, 2026 · NCT07527299Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax
RecruitingObservational study
Ages 18 to 110 · All sexes · Updated Oct 29, 2026 · NCT05724121A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07217067BOdygUardian MOnitoriNg for ReCurrencE of AF
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07671677Globe Registry: Globe® Pulsed Field System Registry Study for Treating Patients With Symptomatic Atrial Fibrillation
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT07651852Evaluation of the FARAFLEX Mapping and Pulsed Field Ablation System in Subjects With Atrial Fibrillation
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT07575269Repeatable Evaluation of Functional Intra-procedural Signals for Effect in Pulsed Field Ablation REFINE-PFA
RecruitingObservational study
Ages 21 and older · All sexes · Updated Oct 21, 2026 · NCT07275151Pericardiotomy in Cardiac Surgery
Recruiting
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT06486636Comparison of Two Pulse Field Ablation Systems for AF Ablation
Recruiting
Ages 18 to 89 · All sexes · Updated Oct 20, 2026 · NCT07883629Tulane iPredict, Prevent Study to Evaluate the Progression of Atrial Myopathy.
RecruitingObservational study
Ages 18 to 79 · All sexes · Updated Oct 20, 2026 · NCT04703166A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Oct 20, 2026 · NCT07625215Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)
Recruiting
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT07298473Elite AF IDE Trial (Elite AF)
Recruiting
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07287436Bachmann's Bundle Versus Right Atrial Appendage Pacing
Recruiting
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07874763From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.