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MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics
RecruitingHealthy volunteers welcome
MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics and Association of Intracranial CSF Flow With Brain Function
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * A healthy control will be defined as an otherwise healthy person who does not have a medical condition that affects brain function or have problems with concentration, memory, balance, or coordination. * Patients who have a suspected diagnosis of altered CSF dynamics including but not limited to normal pressure hydrocephalus will be referred to Dr. Cogswell by their care team to be included in the study. Conditions of altered CSF dynamics include obstructive and non-obstructive hydrocephalus and may be associated with headaches and/or decreased cognitive function. * Similarly, patients with impaired cognitive function including but not limited to Alzheimer's disease will be referred to Dr. Cogswell by their care team to be included in the study. Exclusion Criteria: * Subjects with non-MRI compatible devices * required sedation * women who may be pregnant will be excluded. * The first 10 subjects with normal pressure hydrocephalus will not have previously been shunted.
About the study
The Researchers are trying to test a MR imaging method for detection of Cerebral Spinal Fluid (CSF) flow in the brain to help diagnosis and better understand diseases that affect brain function.
What is being tested
- MRI screening form (other)
- Urine pregnancy test (diagnostic test)
- MR brain (diagnostic test)
Sponsor: Mayo Clinic · Participants: 50 · Started: Oct 31, 2019
Contact the study team
- Suson (Sue) Walsh · Phone: 507-293-0039
Official record on ClinicalTrials.gov — NCT04099823
Locations in the U.S.
| Minnesota | Mayo Clinic, Rochester |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.