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RCT: Early Feeding After PEG Placement

A Randomized Controlled Trial to Reduce Periprocedural Fasting in Ventilated Trauma and Surgical Intensive Care Patients

Who can join

Ages 18 to 100 · All sexes

Inclusion Criteria:

* Adult subjects over 18 years of age
* Negative pregnancy test for women participants of child-bearing age
* Mechanically ventilated surgical and trauma patients with clinical indication for PEG tube placement
* Tolerating tube feeds at goal prior to procedure

Exclusion Criteria:

* Patients with aberant gastrointestinal anatomy
* Patients with gastrointestinal motility disorders
* Patients with feeding intolerance prior to PEG tube procedure
* Pregnant women, children, or other vulnerable populations
* Clinical contraindications for PEG tube placement
* PEG performed in setting other than ICU at bedside

About the study

Randomized controlled trial to establish evidence on which to base timing of enteral feeding after bedside PEG placement in ventilated Trauma and Surgical ICU patients.

What is being tested

• noFast: Start tube feeds within 1 hour of procedure (dietary supplement)

Sponsor: Carilion Clinic · Participants: 1,200 · Started: Sep 19, 2019

Contact the study team

• Katie L. Bower, MD · Phone: 540-981-7434
• Jordan Darden, PhD · Phone: 540-529-7792

Official record on ClinicalTrials.gov — NCT04110613

Locations in the U.S.

Conditions

• Critical Illness
• Malnutrition

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.