Home › Pain After Surgery › NCT04130464
Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
The Impact of the Continuous Infusion of Intraperitoneal Analgesics on Postoperative Pain After Minimally Invasive Hysterectomy: a Randomized Controlled Trial
Who can join
Ages 18 to 65 · Women · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Hysterectomy planned for a benign gynecologic reason (no evidence of, or concern for, malignancy in the cervix, uterus, tubes or ovaries. Benign gynecologic reasons to have a hysterectomy include fibroids, abnormal uterine bleeding, endometriosis, and pelvic pain.) * Patient is scheduled to have surgery with a fellowship trained minimally invasive gynecologic surgeons at one of the study sites. * Patient is planned for a robotic assisted total laparoscopic hysterectomy (RA-TLH) or a total laparoscopic hysterectomy (TLH). * Patient is capable of informed consent. * Patient is capable of completing the questionnaires. Exclusion Criteria: * Concern for malignancy * The procedure is scheduled outside MIGS department. * Allergy to any study related medication (i.e. Ketorolac and Ropivacaine) * Patient is enrolled in another pain management study.
About the study
The study is a prospective, double-blinded, placebo-controlled multi-center trial to measure if postoperative pain and the amount of narcotics used are reduced by a clinically significant amount in women undergoing minimally invasive hysterectomy receiving a continuous infusion of intraperitoneal (IP) local anesthetic (LA) or a continuous infusion of LA combined with an NSAID compared with a control group who receives only 0.9% normal saline.
What is being tested
- Ropivacaine Infusion from ON-Q Pump (drug)
- Ropivacaine + Ketorolac Infusion from ON-Q Pump (drug)
- Normal Saline Infusion from ON-Q Pump (drug)
Sponsor: Ying Liu · Participants: 120 · Started: Sep 30, 2019
Contact the study team
- Radwa Aly · Phone: 202 677 6209
Official record on ClinicalTrials.gov — NCT04130464
Locations in the U.S.
| District of Columbia | MedStar Washington Hospital Center, Washington D.C. The GW Medical Faculty Associates, Washington D.C. |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.