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Pain After Surgery clinical trials recruiting in the U.S.

116 studies for Pain After Surgery are recruiting participants at sites across the United States.

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Recently updated studies

Chronic Postsurgical Pain

RecruitingObservational study
Ages 5 to 17 · All sexes · Updated Sep 25, 2026 · NCT05764681

Latinx Children and Surgery

RecruitingHealthy volunteers welcome
Ages 2 to 12 · All sexes · Updated Sep 24, 2026 · NCT06020677

Post-op Prednisone and Glucose Monitoring in TKA

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07630896

Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release

RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Sep 24, 2026 · NCT07840183

Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06094257

QL Block in Laparoscopic Myomectomy

RecruitingPhase 4
Ages 18 to 45 · Women · Updated Sep 11, 2026 · NCT05979493

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05991453

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05722002

Aromatherapy and Its Impact on Preoperative Anxiety, Postoperative Pain, and Patient Experience

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07771205

Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07689162

Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

Recruiting
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07218133

Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy

RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 65 · Women · Updated Aug 13, 2026 · NCT06483659

Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia

RecruitingPhase 4
Ages 4 to 6 · All sexes · Updated Aug 12, 2026 · NCT06757075

Maternal Mindfulness: Depression and Postpartum Pain

RecruitingHealthy volunteers welcome
Ages 18 to 45 · Women · Updated Aug 6, 2026 · NCT05400382

Rectus Sheath Block in Cardiac Surgery

Recruiting
Ages 18 to 85 · All sexes · Updated Jul 31, 2026 · NCT05833048

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

Recruiting
Ages 22 to 80 · All sexes · Updated Jul 31, 2026 · NCT04144972

Autonomic Neural Blockade in Bariatric Surgery

Recruiting
Ages 18 to 90 · All sexes · Updated Jul 29, 2026 · NCT07104825

Dextenza in the Post-op Management of Vitreoretinal Surgeries

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04371445

iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery

RecruitingHealthy volunteers welcome
Ages 15 to 20 · All sexes · Updated Jul 28, 2026 · NCT07731295

RADA16 for Adult Tonsillectomy

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT07060495

Impact of RADA16 Use on Outcomes Following Tonsillectomy in Children

RecruitingPhase 2
Ages 3 to 17 · All sexes · Updated Jul 22, 2026 · NCT07188779

Methadone for Post-operative Spine Surgery

RecruitingPhase 4
Ages 18 to 120 · All sexes · Updated Jul 20, 2026 · NCT07517679

Identifying Biomarkers Related to Opioid Use and Pain Response Following Traumatic Injury and Surgery

RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 17, 2026 · NCT07693270

Sex Hormones, Postoperative Pain and Opioid Use

RecruitingObservational study
Ages 11 to 16 · Women · Updated Jul 13, 2026 · NCT06023225

Patient Reported Experiences With Sparing External Oblique Fascia Vs Standard Inguinal Orchiectomy

Recruiting
Ages 18 and older · Men · Updated Jul 10, 2026 · NCT06828185

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.