Home › Polycystic Ovary Syndrome › NCT04149496
IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer
A Prospective Series of IVF Cases Utilizing in Vitro Maturation (IVM) With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Embryo Transfer Using a Subsequent Frozen Embryo Transfer Cycle
Who can join
Ages 18 to 38 · Women
Full eligibility criteria
Inclusion Criteria: * PCO pattern with \> 25 antral follicles * AMH \> 3.5 Exclusion Criteria: * BMI \> 35 * body morphology making transvaginal retrieval difficult or impossible * complicating medical condition making pregnancy or IVF relatively contra-indicated
About the study
A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols include the use of the Steiner-Tan needle to optimize oocyte environment during oocyte retrieval, use of oral medications and very low doses of FSH, and delayed embryo transfer during subsequent warmed cryo-preserved embryo transfer. Eligible patient have a PCO pattern in their ovaries during transvaginal ultrasound.
What is being tested
- in vitro maturation of oocytes (combination product)
Sponsor: Bruce Rose, MD · Participants: 300 · Started: May 10, 2019
Contact the study team
- Bruce I Rose, MD, PhD · Phone: 904-260-0352
- Samuel Brown, MD · Phone: 904-260-0352
Official record on ClinicalTrials.gov — NCT04149496
Locations in the U.S.
| Florida | Brown Fertility, Jacksonville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.