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Polycystic Ovary Syndrome clinical trials recruiting in the U.S.
20 studies for Polycystic Ovary Syndrome are recruiting participants at sites across the United States.
Polycystic ovary syndrome (PCOS) happens when a woman's ovaries or adrenal glands produce more male hormones than normal. Learn the symptoms of PCOS and treatments.
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Recently updated studies
Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome
RecruitingPhase 3
Ages 12 to 35 · Women · Updated Aug 31, 2026 · NCT05819853PCOS and Brain Health
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 45 · Women · Updated Aug 21, 2026 · NCT07727512Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)
Recruiting
Ages 11 to 17 · Women · Updated Aug 21, 2026 · NCT07780188This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms.
Recruiting
Ages 18 to 40 · Women · Updated Aug 13, 2026 · NCT07764328Health-Related Quality of Life and Metabolic Outcomes in PCOS
RecruitingHealthy volunteers welcome
Ages 18 to 49 · Women · Updated Jul 1, 2026 · NCT07571915Combined Oral Contraceptive Pill and Resistance Starch
RecruitingPhase 2
Ages 18 to 40 · Women · Updated Jun 1, 2026 · NCT06852365Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation Pilot
Recruiting
Ages 18 to 40 · Women · Updated May 8, 2026 · NCT07227363Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT05950282ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence
Recruiting
Ages 8 and older · Women · Updated Mar 19, 2026 · NCT07102797Protein and Polycystic Ovary Syndrome (PCOS)
RecruitingHealthy volunteers welcome
Ages 18 to 50 · Women · Updated Sep 8, 2025 · NCT07158723Appetite Response to Meals With Different Protein Sources in Women With PCOS
Recruiting
Ages 18 to 50 · Women · Updated Sep 2, 2025 · NCT07142603Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism
RecruitingEarly phase 1Healthy volunteers welcome
Ages 10 to 17 · Women · Updated Aug 5, 2025 · NCT00929006Hyperandrogenemia and Altered Day-night LH Pulse Patterns
RecruitingEarly phase 1Healthy volunteers welcome
Ages 10 to 17 · Women · Updated Aug 5, 2025 · NCT03068910Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 30 · Women · Updated Aug 5, 2025 · NCT03401047Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?
RecruitingEarly phase 1Healthy volunteers welcome
Ages 10 to 17 · Women · Updated Aug 5, 2025 · NCT04723862Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients
Recruiting
Ages 18 to 64 · All sexes · Updated Jul 25, 2025 · NCT06049420In Vitro Maturation of Human Eggs
Recruiting
Up to age 38 · Women · Updated Oct 9, 2024 · NCT06633120Apple Women's Health Study
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 3, 2024 · NCT04196595The PCOS Challenge Study
RecruitingObservational studyHealthy volunteers welcome
Ages 12 to 80 · Women · Updated Apr 4, 2023 · NCT05797909IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer
Recruiting
Ages 18 to 38 · Women · Updated Nov 4, 2019 · NCT04149496From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.