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Polycystic Ovary Syndrome clinical trials recruiting in the U.S.

20 studies for Polycystic Ovary Syndrome are recruiting participants at sites across the United States.

Polycystic ovary syndrome (PCOS) happens when a woman's ovaries or adrenal glands produce more male hormones than normal. Learn the symptoms of PCOS and treatments.

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Recently updated studies

Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome

RecruitingPhase 3
Ages 12 to 35 · Women · Updated Aug 31, 2026 · NCT05819853

PCOS and Brain Health

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 45 · Women · Updated Aug 21, 2026 · NCT07727512

Health-Related Quality of Life and Metabolic Outcomes in PCOS

RecruitingHealthy volunteers welcome
Ages 18 to 49 · Women · Updated Jul 1, 2026 · NCT07571915

Combined Oral Contraceptive Pill and Resistance Starch

RecruitingPhase 2
Ages 18 to 40 · Women · Updated Jun 1, 2026 · NCT06852365

Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation Pilot

Recruiting
Ages 18 to 40 · Women · Updated May 8, 2026 · NCT07227363

Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT05950282

ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence

Recruiting
Ages 8 and older · Women · Updated Mar 19, 2026 · NCT07102797

Protein and Polycystic Ovary Syndrome (PCOS)

RecruitingHealthy volunteers welcome
Ages 18 to 50 · Women · Updated Sep 8, 2025 · NCT07158723

Appetite Response to Meals With Different Protein Sources in Women With PCOS

Recruiting
Ages 18 to 50 · Women · Updated Sep 2, 2025 · NCT07142603

Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism

RecruitingEarly phase 1Healthy volunteers welcome
Ages 10 to 17 · Women · Updated Aug 5, 2025 · NCT00929006

Hyperandrogenemia and Altered Day-night LH Pulse Patterns

RecruitingEarly phase 1Healthy volunteers welcome
Ages 10 to 17 · Women · Updated Aug 5, 2025 · NCT03068910

Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome

RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 30 · Women · Updated Aug 5, 2025 · NCT03401047

Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?

RecruitingEarly phase 1Healthy volunteers welcome
Ages 10 to 17 · Women · Updated Aug 5, 2025 · NCT04723862

Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients

Recruiting
Ages 18 to 64 · All sexes · Updated Jul 25, 2025 · NCT06049420

In Vitro Maturation of Human Eggs

Recruiting
Up to age 38 · Women · Updated Oct 9, 2024 · NCT06633120

Apple Women's Health Study

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 3, 2024 · NCT04196595

The PCOS Challenge Study

RecruitingObservational studyHealthy volunteers welcome
Ages 12 to 80 · Women · Updated Apr 4, 2023 · NCT05797909

IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer

Recruiting
Ages 18 to 38 · Women · Updated Nov 4, 2019 · NCT04149496

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.