Home › Barrett Esophagus › NCT04214119

EsophaCap for the Detection of Early Esophageal Carcinoma

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Undergoing esophagogastroduodenoscopy at Johns Hopkins Hospital from 1/2016 to 12/2025
* Age greater than 18 years
* Patients must be able to swallow a capsule

Exclusion Criteria:

* Patients in either arm with extra-esophageal malignancies including head and neck and gastric cancer
* Patients who have undergone esophagectomy
* Patients who have undergone radiation to the chest
* Patients who are younger than 18
* Patients with esophageal stents
* Patients with esophageal strictures disabling passage of the capsule

About the study

This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carcinoma), and gastric cancer via sponge cytology.

Sponsor: Johns Hopkins University · Participants: 2,500 · Started: Jan 12, 2016

Contact the study team

• Stephen J Meltzer, M.D. · Phone: 4105026071

Official record on ClinicalTrials.gov — NCT04214119

Locations in the U.S.

Conditions

• Barrett Esophagus
• Esophageal Cancer
• Stomach Cancer

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.