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Ketamine for Post-operative Analgesia in Hemorrhoidectomy

RecruitingPhase 4

Intra-operative Use of Ketamine for Post-Operative Analgesia in Patients Undergoing Hemorrhoidectomy: A Prospective, Randomized Controlled Trial.

Who can join

Ages 18 to 100 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Adults aged 18-100
* Undergoing a hemorrhoidectomy for Grade III or IV hemorrhoids.

Exclusion Criteria:

* Inability to undergo general anesthesia
* Contraindications to hemorrhoidectomy
* History of schizophrenia or other hallucinatory psychiatric illnesses
* History of psychosis
* Chronic narcotic usage defined as either having a pain contract with a pain management specialist and no narcotic usage for one month prior to hemorrhoidectomy.

About the study

This is a prospective, randomized study of ketamine versus no ketamine in approximately 100 patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids. The participants will be blinded to which treatment arm they are assigned, because participants will be under anesthesia when the ketamine is administered. The investigators will know whether the participant receives ketamine or not.

What is being tested

Sponsor: University of Oklahoma · Participants: 100 · Started: Jun 15, 2020

Contact the study team

Official record on ClinicalTrials.gov — NCT04248205

Locations in the U.S.

OklahomaUniversity of Oklahoma Health Sciences Center, Oklahoma City

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.