Home › Back Pain › NCT04326192

Brown Adipose Tissue Activation by Spinal Cord Stimulation

Who can join

Ages 21 to 70 · All sexes

Inclusion Criteria:

1. Age: 21-70 years
2. Persistent neuropathic leg and back pain
3. Subjects who are already planning to undergo SCS for pain
4. Subjects who have not received a prior SCS trial for pain
5. Subjects with a BMI of 25-45, using formula; weight (lb) / \[height (in)\]2 x 703

Exclusion Criteria:

1. Not considering SCS for pain
2. Forensic patient
3. Taking beta blockers
4. Weight change \> 5% within last 3 months
5. Habitual tobacco use
6. Habitual excessive alcohol use
7. Pregnancy
8. Decisionally impaired adults
9. Children
10. Neonates
11. Subjects with a BMI of \<25 or \>45

About the study

The objective of this study is to investigate and utilize spinal cord stimulation (SCS) as an effective approach to eliciting weight loss and potentially alleviating Type 2 diabetes mellitus (DM), as evidenced by increasing metabolism of adipose tissue.

What is being tested

• Research electrode (device)

Sponsor: Oregon Health and Science University · Participants: 10 · Started: Feb 19, 2021

Contact the study team

• Kim Burchiel, MD · Phone: 503-494-4314

Official record on ClinicalTrials.gov — NCT04326192

Locations in the U.S.

Conditions

• Back Pain
• Weight Loss Surgery
• Type 2 Diabetes
• Obesity
• Diabetes

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.