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Type 2 Diabetes clinical trials recruiting in the U.S.
240 studies for Type 2 Diabetes are recruiting participants at sites across the United States.
Type 2 Diabetes, previously referred to as Adult Onset Diabetes, is the more common type. Risk factors include obesity and family history.
Cities with the most studies
- San Antonio, TX36 studies
- Houston, TX30 studies
- Orlando, FL24 studies
- Boston, MA20 studies
- Miami, FL19 studies
- Chicago, IL19 studies
- Columbus, OH18 studies
- Dallas, TX18 studies
- Atlanta, GA17 studies
- Las Vegas, NV17 studies
- Birmingham, AL16 studies
- New York City, NY16 studies
- San Diego, CA16 studies
- Philadelphia, PA15 studies
- Los Angeles, CA15 studies
- Arlington, VA15 studies
- Jacksonville, FL14 studies
- Havelock, NC13 studies
- Cincinnati, OH12 studies
- Indianapolis, IN12 studies
- Washington, DC12 studies
- Aurora, CO11 studies
- Durham, NC11 studies
- Omaha, NE11 studies
- Long Beach, CA11 studies
- Austin, TX11 studies
- Kansas City, MO11 studies
- Oklahoma City, OK10 studies
- Baltimore, MD10 studies
- Little Rock, AR10 studies
- New Haven, CT10 studies
- Albuquerque, NM10 studies
- Concord, CA10 studies
- Ann Arbor, MI10 studies
- Tucson, AZ10 studies
- Salt Lake City, UT10 studies
- Pittsburgh, PA10 studies
- Winston-Salem, NC9 studies
- Phoenix, AZ9 studies
- Hialeah, FL9 studies
By state
- Alabama22 studies
- Arizona21 studies
- Arkansas11 studies
- California66 studies
- Colorado16 studies
- Connecticut13 studies
- District of Columbia7 studies
- Florida47 studies
- Georgia34 studies
- Hawaii6 studies
- Idaho12 studies
- Illinois29 studies
- Indiana19 studies
- Iowa9 studies
- Kansas14 studies
- Kentucky12 studies
- Louisiana15 studies
- Maryland26 studies
- Massachusetts29 studies
- Michigan26 studies
- Minnesota17 studies
- Mississippi9 studies
- Missouri20 studies
- Montana4 studies
- Nebraska14 studies
- Nevada17 studies
- New Jersey15 studies
- New Mexico11 studies
- New York33 studies
- North Carolina35 studies
- North Dakota6 studies
- Ohio40 studies
- Oklahoma13 studies
- Oregon7 studies
- Pennsylvania30 studies
- Rhode Island3 studies
- South Carolina20 studies
- South Dakota3 studies
- Tennessee17 studies
- Texas57 studies
- Utah18 studies
- Virginia25 studies
- Washington20 studies
- West Virginia7 studies
- Wisconsin9 studies
Recently updated studies
NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study
Recruiting
All ages · All sexes · Updated Sep 29, 2026 · NCT06593327A Randomized Controlled Trial of Diabetes Screening Immediately Postpartum (DIP) and Follow Up PP CARE
Recruiting
Ages 18 and older · Women · Updated Sep 29, 2026 · NCT05909046A Study of PATAS Using Single Ascending Doses in Healthy Volunteers and Multiple Ascending Doses in Diabetic Subjects
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Sep 29, 2026 · NCT07223333Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Sep 28, 2026 · NCT07399678Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes
Recruiting
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06836479A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07595549A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
RecruitingHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07776509ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
Recruiting
Ages 8 to 21 · All sexes · Updated Sep 23, 2026 · NCT05463289A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07783802A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)
RecruitingHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT02969798Phenotyping Genetic Risk for Type 2 Diabetes
RecruitingHealthy volunteers welcome
Ages 10 to 70 · All sexes · Updated Sep 21, 2026 · NCT04024631Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance
RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 45 · All sexes · Updated Sep 18, 2026 · NCT07494084Improving the Collaborative Health of Adult Dyads
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05370014Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort Study
RecruitingObservational studyHealthy volunteers welcome
Ages 12 to 25 · All sexes · Updated Sep 17, 2026 · NCT06730113Plant-Based Online Weight Loss Through Education and Resources Program and Study
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07095543A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07754461Cooking Health-Oriented Meals to Prevent Dementia and Diabetes
RecruitingHealthy volunteers welcome
Ages 50 to 75 · All sexes · Updated Sep 16, 2026 · NCT07661368A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Sep 16, 2026 · NCT07723833A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 16, 2026 · NCT07465224EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07064473LINK-IT: Leveraging vIdeos and commuNity Health worKers to Improve Diabetes OuTcomes
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06319716From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.