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Type 2 Diabetes clinical trials recruiting in the U.S.
245 studies for Type 2 Diabetes are recruiting participants at sites across the United States.
Type 2 Diabetes, previously referred to as Adult Onset Diabetes, is the more common type. Risk factors include obesity and family history.
Cities with the most studies
- San Antonio, TX37 studies
- Houston, TX31 studies
- Orlando, FL25 studies
- Atlanta, GA21 studies
- San Diego, CA21 studies
- Boston, MA20 studies
- Miami, FL20 studies
- Chicago, IL19 studies
- Arlington, VA19 studies
- Los Angeles, CA18 studies
- Dallas, TX18 studies
- Columbus, OH17 studies
- Las Vegas, NV17 studies
- New York City, NY17 studies
- Birmingham, AL16 studies
- Philadelphia, PA16 studies
- Jacksonville, FL15 studies
- Havelock, NC14 studies
- Austin, TX14 studies
- Aurora, CO13 studies
- Indianapolis, IN13 studies
- Washington, DC13 studies
- Tucson, AZ13 studies
- Baltimore, MD13 studies
- Omaha, NE12 studies
- Cincinnati, OH12 studies
- Kansas City, MO11 studies
- Hialeah, FL11 studies
- Deltona, FL11 studies
- Salt Lake City, UT11 studies
- Pittsburgh, PA11 studies
- Edison, NJ10 studies
- Little Rock, AR10 studies
- Wichita, KS10 studies
- Concord, CA10 studies
- Sacramento, CA10 studies
- Memphis, TN10 studies
- New Haven, CT10 studies
- Durham, NC10 studies
- Long Beach, CA10 studies
By state
- Alabama22 studies
- Arizona25 studies
- Arkansas11 studies
- California74 studies
- Colorado18 studies
- Connecticut16 studies
- District of Columbia9 studies
- Florida49 studies
- Georgia37 studies
- Hawaii8 studies
- Idaho14 studies
- Illinois32 studies
- Indiana18 studies
- Iowa11 studies
- Kansas16 studies
- Kentucky12 studies
- Louisiana18 studies
- Maryland28 studies
- Massachusetts28 studies
- Michigan25 studies
- Minnesota18 studies
- Mississippi8 studies
- Missouri21 studies
- Montana4 studies
- Nebraska15 studies
- Nevada17 studies
- New Jersey15 studies
- New Mexico11 studies
- New York34 studies
- North Carolina37 studies
- North Dakota6 studies
- Ohio39 studies
- Oklahoma13 studies
- Oregon7 studies
- Pennsylvania33 studies
- Rhode Island3 studies
- South Carolina19 studies
- South Dakota3 studies
- Tennessee20 studies
- Texas59 studies
- Utah19 studies
- Virginia29 studies
- Washington23 studies
- West Virginia9 studies
- Wisconsin9 studies
Recently updated studies
Evaluation of MiniMed Next Generation Extended Wear Sensors and Algorithm in Patients With Type 1 and Type 2 Diabetes
Recruiting
Ages 2 to 80 · All sexes · Updated Nov 13, 2026 · NCT07864168A Study Evaluating the Safety of Inavolisib and Fulvestrant With or Without Palbociclib in Participants With Advanced Breast Cancer (ABC) and Type 2 Diabetes
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07748208A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07754461A Study to Compare Different Doses of Tifeglipron (RO7795081) With Placebo or Semaglutide in People With Type 2 Diabetes
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07112872EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07064473A Study to Investigate Safety, Tolerability, PK, and PD of AZD4248 in Healthy Participants, Participants With CKD and Type 2 Diabetes, Assess Home Measurements of Creatinine in a Non-Interventional Cohort, and Assess the Effect of AZD4248 on the PK of Midazolam and Metformin in Healthy Participants
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Nov 12, 2026 · NCT07024823Food Insecurity Reduction & Strategy Team
Recruiting
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06329375Gut Microbiota in Metabolic Surgery
RecruitingObservational study
Ages 21 to 65 · All sexes · Updated Nov 9, 2026 · NCT05000996Permissive Versus Strict Intrapartum Glucose Management in Type 1 and Type 2 Diabetes (PRISM)
RecruitingPhase 4
Ages 18 and older · Women · Updated Nov 9, 2026 · NCT07293715Adapting and Assessing the Feasibility of a Telehealth Diabetes Prevention Program for Hispanic Adolescents
RecruitingHealthy volunteers welcomeMentions payment for participants
Ages 14 to 16 · All sexes · Updated Nov 9, 2026 · NCT06943001Continuous Glucose Monitoring for Self-Management of Type 2 Diabetes in Young Adults
Recruiting
Ages 18 to 45 · All sexes · Updated Nov 9, 2026 · NCT07065721A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07776509A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07351058A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes
RecruitingPhase 3
Ages 10 to 17 · All sexes · Updated Nov 5, 2026 · NCT07668336Linking Education, Produce Provision, and Community Referrals to Improve Diabetes Care (LINK)
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT05472441Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07866066A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07843485A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07595549A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 Diabetes
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07881458A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07282600Clinical Decision Support for SGLT2i After AKI in Type 2 Diabetes
Recruiting
Ages 30 to 75 · All sexes · Updated Nov 4, 2026 · NCT07868666A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2 Diabetes (VESPER-OA 2)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07915609A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Nov 4, 2026 · NCT06897475A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07783802Culturally Tailored Program for Food-Insecure Adults: SPICE-D
Recruiting
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT07361341From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.