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The Olmsted NAFLD Epidemiology Study (TONES)

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Olmsted County residents at the time of search
* Age 18 or older
* No personal history of NAFLD diagnosis (administrative codes)

Exclusion Criteria:

* Alcohol in excess (more than 20 gm per week in women and 30 gm per week in men)
* Currently pregnant
* Have contraindications to MRI (MRI incompatible implanted devices, severe claustrophobia)

About the study

Researchers are assessing the prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) in the population and assembling a well-characterized cohort of adults with NAFLD and NASH to validate models of NAFLD diagnosis and determine long-term outcomes.

What is being tested

• Magnetic Resonance Elastography (diagnostic test)
• Blood draw (other)
• Liver biopsy (procedure)
• Fibro Scan (procedure)

Sponsor: Mayo Clinic · Participants: 800 · Started: Oct 10, 2020

Contact the study team

• Jodie A Cogswell · Phone: 507-266-3995

Official record on ClinicalTrials.gov — NCT04365855

Locations in the U.S.

Conditions

• Steatotic Liver Disease

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.