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Collection of Information to Better Understand Young Onset Colorectal Cancer

RecruitingObservational study

Young Onset Gastrointestinal Cancer Prospective Registry

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

Participant Inclusion Criteria for database and questionnaire (YOGI)

* Histological or cytological diagnosis of gastrointestinal cancer
* 18 - 49 years old at time of consent
* No Known hereditary CRC or other cancer predisposition syndrome (stool collection cohort only)
* No history of inflammatory bowel disease (stool collection cohort only)
* No prior diagnosis of gastrointestinal cancer (stool collection cohort only)

Participant Inclusion Criteria for database and questionnaire (Controls)

* Histological or cytological diagnosis of colorectal adenocarcinoma
* No previous treatment for CRC (including surgery, chemotherapy, immunotherapy or radiation)
* Age 50 or older at time of consent
* No Known hereditary CRC or other cancer predisposition syndrome
* No history of inflammatory bowel disease
* No prior diagnosis of CRC

About the study

The purpose of this registry study is to create a database-a collection of information-for better understanding young onset colorectal cancer. Colorectal cancer patients are considered to have young onset colorectal cancer if they are diagnosed with their cancer before the age of 50. Researchers will use the information from this database to learn more about how young onset colorectal cancer may be similar to or different from colorectal cancer that is diagnosed later in life. Researchers will also use information from the database for current and future research on young onset colorectal cancer.

What is being tested

Sponsor: Memorial Sloan Kettering Cancer Center · Participants: 1,366 · Started: Jul 22, 2020

Contact the study team

Official record on ClinicalTrials.gov — NCT04489238

Locations in the U.S.

New JerseyMemorial Sloan Kettering Basking Ridge (All Protocol Activities), Basking Ridge
Memorial Sloan Kettering Monmouth, Middletown
Memorial Sloan Kettering Bergen, Montvale
New YorkMemorial Sloan Kettering Cancer Center @ Commack, Commack
Memorial Sloan Kettering Westchester, Harrison
MSK at Ralph Lauren, New York
Memorial Sloan Kettering Cancer Center, New York
Memorial Sloan Kettering Nassau, Rockville Centre

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.