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Blood Flow Restriction Training After Patellar INStability

Recruiting

Blood Flow Restriction Training After Patellar INStability (BRAINS Trial)

Who can join

Ages 14 to 40 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Diagnosis of traumatic patellar instability (either primary or recurrent) determined by an American Board of Family Medicine certified physician with a Certificate of Added Qualifications in Sports Medicine or licensed Physical Therapist utilizing clinical examination, radiographic imaging, and patients' reports of instability
* Age 14 to 40 years
* Skeletally mature with closed growth plates visualized by radiograph
* A score of 80 or more on the Sports Activity Scale, which corresponds to participating in "running, twisting, turning (tennis, racquetball, handball, ice hockey, field hockey, skiing, wrestling)" at least 1-3 times per week
* Desire to resume pre-injury activity level

Exclusion Criteria:

* Concomitant osteochondral lesion requiring surgical fixation
* Radiographic evidence of osteoarthritis (\< Kellgren-Lawrence Grade 2)
* Previous ipsilateral or contralateral knee surgery
* Most recent instability event more than 3 months before enrollment
* History of any inflammatory disorder
* BMI \> 35 kg/m2
* Diabetes or uncontrolled hypertension
* Varicose veins or a history of personal or immediate family history (parental or sibling) of deep vein thrombosis
* Pre-existing conditions or previous surgeries that effect the ability to walk
* Planned trips or vacations that will result in the inability to attend 4 consecutive physical therapy sessions

About the study

This research study is designed to allow health care professionals and researchers to answer many questions about whether a new type of physical therapy called blood flow restriction training (called BFRT) will improve recovery for those with patellar instability.

What is being tested

Sponsor: Caitlin Conley · Participants: 78 · Started: Sep 9, 2020

Contact the study team

Official record on ClinicalTrials.gov — NCT04554212

Locations in the U.S.

KentuckyUK Healthcare at Turfland, Lexington
University of Kentucky Biomotion Laboratory, Lexington
MassachusettsCenter for Sports Performance and Research, Foxborough
Foxboro Sports Medicine Clinic, Foxborough

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.