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Cardiogenic Shock Working Group Registry

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Patients must have cardiogenic shock.

Cardiogenic shock is defined by at least one of the two categories below:

1. At least 2 of the following concurrently at any point during the index hospitalization:

   * Cardiac Index \< 2.2
   * PAPI \< 1.0
   * Cardiac Power Output ≤ 0.6
   * MAP \< 60mmHg or a \>30mmHg drop in MAP from baseline
   * SBP \< 90mmHg or a \>30mmHg drop in SBP from baseline
   * Pulse \> 100
2. Require at least one acute mechanical circulatory support device, vasopressor or inotrope to maintain values above the above target.

Post-cardiotomy patients must meet the inclusion criteria 72 hours after their surgery to be included in this registry.

About the study

The Cardiogenic Shock Working Group is a multicenter registry where we collect de-identified clinical variables from the medical records and follow-up phone calls of shock patients from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes.

What is being tested

• Vasopressor (drug)
• Inotrope (drug)
• Acute Mechanical Circulatory Support Devices (device)

Sponsor: Tufts Medical Center · Participants: 5,000 · Started: Dec 4, 2017

Contact the study team

• Navin K Kapur, MD · Phone: 6176368252

Official record on ClinicalTrials.gov — NCT04682483

Locations in the U.S.

Conditions

• Cardiogenic Shock
• Heart Failure

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.