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Young Houston Emergency Opioid Engagement System
Houston Emergency Engagement System for Youths and Adolescents
Who can join
Ages 13 to 17 · All sexes
Full eligibility criteria
Inclusion Criteria: * In otherwise good health based on physician assessment and medical history * Drug screen positive for opioids * Patients express a willingness to stop opioid use * Meet Diagnostic and Statistical Manual of Mental Disorders - Text Revision (DSM-IV-TR) criteria for opioid dependence * Patients must be able to speak English * Be agreeable to and capable of signing the informed consent and assent (parent or guardian must consent, minor must assent) Exclusion Criteria: * Non-English-speaking patients * Have a known sensitivity to buprenorphine or naloxone * Be physiologically dependent on alcohol, benzodiazepines, or other drugs of abuse that require immediate medical attention. Other substance use diagnoses are not exclusionary. * Have a medical condition that would, in the opinion of the study physician, make participation medically hazardous, including unstable cardiovascular disease, neurological deficits, trauma, acute hepatitis, stroke, and liver or renal disease) * Be acutely psychotic, severely depressed, and in need of inpatient treatment, or is an immediate suicide risk * Be a nursing or pregnant female
About the study
The Houston Emergency Response Opioid Engagement System for Youths and Adolescents (Young HEROES) is a community-based research program integrating assertive outreach, medication for opioid use disorder (MOUD), behavioral counseling, and peer recovery support. The objective is to compare differences in engagement and retention in treatment for individuals with opioid use disorder. The investigators also intend to understand the prevalence of opioid overdoses and OUD among youth in Houston.
What is being tested
- Buprenorphine, Naloxone Drug Combination (drug)
- Individual Counseling (behavioral)
- Peer Recovery Support Services (behavioral)
- Support Group (behavioral)
- Referral to Medication Management (behavioral)
- Assertive Outreach (behavioral)
Sponsor: The University of Texas Health Science Center, Houston · Participants: 250 · Started: Apr 19, 2021
Contact the study team
- James R Langabeer, PhD · Phone: 713-500-3925
- Meredith M O'Neal, MA · Phone: 713-500-3624
Official record on ClinicalTrials.gov — NCT04811014
Locations in the U.S.
| Texas | The University of Texas Health Science Center at Houston, Houston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.