Home › Metabolic Syndrome › NCT04893226
Circadian Rhythms in Postmenopausal Women
Who can join
Ages 45 to 65 · Women · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * postmenopausal women * age 45-65 years * prediabetic or have at least 2 features of metabolic syndrome Exclusion Criteria: * on hormone therapy * diabetes * heart disease * alcohol consumption of \>2 drinks per day * significant circadian disruption * having care-taking responsibilities that significantly affect sleep * shift work or irregular lifestyle * uncontrolled sleep apnea or other uncontrolled sleep disorder * extreme early or late chronotypes * significant psychiatric disorders * taking ADHD medications * diagnosed dysregulated eating behaviors * smoking \>5 cigarettes/day or 30 pack-year history * participating in formal weight loss program * not weight stable
About the study
This is a randomized, parallel two-arm clinical trial design to study the efficacy of time-restricted feeding on metabolic risk in postmenopausal women, who may be particularly vulnerable to disruption of circadian eating rhythms and the associated metabolic dysfunction. It is hypothesized that time-restricted feeding will improve insulin sensitivity, glucose tolerance, body weight, and other metabolic parameters in metabolically-unhealthy postmenopausal women.
What is being tested
- Time-Restricted Feeding (TRF) (behavioral)
Sponsor: Julie Pendergast · Participants: 164 · Started: Oct 19, 2021
Contact the study team
- Matt Thomas, PhD · Phone: (859) 218-6770
Official record on ClinicalTrials.gov — NCT04893226
Locations in the U.S.
| Kentucky | University of Kentucky, Lexington |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.