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Meal Delivery and Exercise

A Meal Delivery and Exercise Intervention to Increase Resilience in Homebound Older Adults

Who can join

Ages 60 and older · All sexes

Inclusion Criteria:

* homebound (normally unable to leave the home unassisted)
* frail or prefrail by The Fried Frailty Phenotype (FFP)
* medically stable

Exclusion Criteria:

* robust by FFP
* have Mini-Cog score \<3 and/or are unable to follow instructions
* have a pre-diagnosed terminal illness
* unable to ambulate
* unable to use their upper extremities, and/or are already participating in physician-prescribed physical therapy or occupational therapy.

About the study

The purpose of this study is to evaluate the effects of a home-based exercise program administered through Meals on wheels (MOW) on gait speed and frailty status and to assess the association between novel serum biomarkers (70 kilodalton heat shock proteins (HSP70),Macrophage Inflammatory Proteins(MIP1b), soluble IL-6 receptor alpha-chain (sIL-6R)) and established but non-specific frailty biomarkers (Interleukin 6 (IL-6), C-reactive protein (CRP), Tumor necrosis factor (TNF-α)) in frail and prefrail homebound older adults before and after the exercise intervention.

What is being tested

• Meals plus exercise (behavioral)
• Meals only (behavioral)

Sponsor: The University of Texas Health Science Center, Houston · Participants: 100 · Started: Jul 19, 2021

Contact the study team

• Jessica Lee, MD,MS · Phone: 713-500-5457
• Paola Robles Cordova · Phone: (713) 500-7904

Official record on ClinicalTrials.gov — NCT04906759

Locations in the U.S.

Conditions

• Frailty

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.