Home โบ Frailty
Frailty clinical trials recruiting in the U.S.
35 studies for Frailty are recruiting participants at sites across the United States.
Cities with the most studies
By state
- California9 studies
- Colorado5 studies
- Illinois6 studies
- Massachusetts3 studies
- North Carolina4 studies
- Texas3 studies
Recently updated studies
Dose Adjusted Chemoradiotherapy in HPV-Associated Oropharynx Cancer of the Elderly
Recruiting
Ages 65 to 99 ยท All sexes ยท Updated Sep 29, 2026 ยท NCT06309225Fall Prevention Pathways
RecruitingHealthy volunteers welcome
Ages 65 to 85 ยท All sexes ยท Updated Sep 17, 2026 ยท NCT07824141Longevity Metrics AI/ML Development Study
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 9, 2026 ยท NCT07808619100-Year Human Aging Study
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 8, 2026 ยท NCT07563777Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.
Recruiting
Ages 18 and older ยท All sexes ยท Updated Sep 8, 2026 ยท NCT06374537Health Ahead Comparative Effectiveness Study
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 8, 2026 ยท NCT07669168Human Observatory Study
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 8, 2026 ยท NCT07646782Baltimore Longitudinal Study of Aging
RecruitingObservational studyHealthy volunteers welcome
Ages 20 to 120 ยท All sexes ยท Updated Sep 1, 2026 ยท NCT00233272Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older
Recruiting
Ages 50 and older ยท All sexes ยท Updated Aug 27, 2026 ยท NCT05858034The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults
RecruitingPhase 2Healthy volunteers welcome
Ages 65 to 80 ยท All sexes ยท Updated Aug 12, 2026 ยท NCT06027554Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 15, 2026 ยท NCT07029243The Better, Harder, Faster, Stronger Study
RecruitingObservational study
Ages 55 and older ยท Women ยท Updated Jul 15, 2026 ยท NCT07220512Functional Assessment in Liver Transplantation
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Jul 14, 2026 ยท NCT03228290Dual Task Perturbation Training for OAwMCI
RecruitingHealthy volunteers welcome
Ages 55 and older ยท All sexes ยท Updated Jul 8, 2026 ยท NCT04938349A Partnered Evaluation to Improve the Identification and Management of Functional Impairment and Frailty Among Older Veterans in Primary Care Settings
Recruiting
Ages 60 and older ยท All sexes ยท Updated Jun 18, 2026 ยท NCT06404970Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients
Recruiting
Ages 65 and older ยท All sexes ยท Updated Jun 8, 2026 ยท NCT05725928Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV
RecruitingPhase 2
Ages 50 to 80 ยท All sexes ยท Updated May 19, 2026 ยท NCT06554717Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients
Recruiting
Ages 60 and older ยท All sexes ยท Updated Apr 13, 2026 ยท NCT06586970Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults
RecruitingHealthy volunteers welcome
Ages 60 to 80 ยท All sexes ยท Updated Feb 20, 2026 ยท NCT07144527Precision Medicine and Physical Function
Recruiting
Ages 65 to 85 ยท All sexes ยท Updated Feb 17, 2026 ยท NCT05877846Preliminary Testing of Cafe Move for Primary Prevention of Physical Frailty
RecruitingHealthy volunteers welcome
Ages 50 to 85 ยท All sexes ยท Updated Feb 5, 2026 ยท NCT05720507Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Jan 30, 2026 ยท NCT04717869PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery
RecruitingObservational study
Ages 18 and older ยท Women ยท Updated Jan 26, 2026 ยท NCT06089083CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease
RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Jan 2, 2026 ยท NCT05422534Human/Machine Interface: What the HeartMate 3 ยฎ Device Tells Us About the Future
RecruitingObservational study
Ages 18 to 100 ยท All sexes ยท Updated Dec 16, 2025 ยท NCT06039176From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.