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Time Restricted Feeding, Muscle, and Metabolism
Time Restricted Feeding Intervention for Muscle and Metabolic Health (TRIMM)
Who can join
Ages 25 to 50 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Resides in Northwest Arkansas * Age 25-50 years * BMI \> 25 * All ethnicities * Female and male Exclusion Criteria: * Food allergies * Pregnant or breastfeeding * Dietary restrictions (e.g. vegetarian, vegan, etc.) * Trying to lose weight in last 3 months * Pre-existing health conditions related to obesity (e.g. cardiovascular disease, diabetes, hypertension) * Prescription medications related to heart disease or type 2 diabetes * Fear of needles * Smoker or vaping * Currently taking protein supplements or other nutritional supplements which may interfere with study outcomes * Consumes \>4 alcoholic beverages per week
About the study
Effective nutrition strategies for combatting and/or preventing obesity still need to be identified. This has been the case despite the numerous and different approaches that have been taken. Potential targets for combatting/preventing obesity have been identified, but long-term solutions have not emerged. This study uses time restricted feeding to study the role of dietary protein in obesity prevention and/or treatment. The objectives are to determine the role of skeletal muscle mass as a driver of energy-sensing mechanisms and peripheral signals that regulate appetite and energy intake in overweight and obese adults and to determine the effects of protein timing on muscle mass to regulate appetite and energy intake in overweight and obese adults.
What is being tested
- Whey protein supplement (dietary supplement)
- Ketogenic aid (dietary supplement)
- Control group - time restricted feeding only (other)
Sponsor: University of Arkansas, Fayetteville · Participants: 90 · Started: Jun 13, 2021
Contact the study team
- Jamie Baum, PhD · Phone: 479-575-4474
Official record on ClinicalTrials.gov — NCT04949451
Locations in the U.S.
| Arkansas | University of Arkansas, Fayetteville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.