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Overweight clinical trials recruiting in the U.S.

209 studies for Overweight are recruiting participants at sites across the United States.

Cities with the most studies

By state

Recently updated studies

Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)

RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 60 ยท Women ยท Updated Nov 12, 2026 ยท NCT03407079

Testing Just-in-Time Adaptive Interventions (JITAIs) to Prevent Goal Disengagement in Response to Weight Regain

Recruiting
Ages 18 to 75 ยท All sexes ยท Updated Nov 10, 2026 ยท NCT07708064

Efficacy and Safety of Olatorepatide Versus Placebo in Adults With Moderate to Severe Hidradenitis Suppurativa Living With Overweight or Obesity

RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Nov 10, 2026 ยท NCT07830329

Time Restricted Eating (TRE) in Bipolar Disorder

Recruiting
Ages 18 to 65 ยท All sexes ยท Updated Nov 10, 2026 ยท NCT07211217

Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight

RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07871409

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07351045

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07351058

Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes

RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Nov 6, 2026 ยท NCT07685808

Metabolic Health, Bones and Nuts During Weight Loss in Adults

RecruitingHealthy volunteers welcome
Ages 50 to 75 ยท All sexes ยท Updated Nov 6, 2026 ยท NCT06949280

A Study to Learn How Different Forms of the Study Medicine Called Berobenatide is Taken up Into the Blood in Adults With Overweight or Obesity

RecruitingPhase 1Healthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Nov 6, 2026 ยท NCT07876531

Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07866066

A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07843498

A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07843485

A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1)

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07919678

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07794579

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07595549

Confident Moves Intervention Efficacy Trial: Obesity Care Settings

Recruiting
Ages 18 to 64 ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07623772

A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 Diabetes

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07881458

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07282600

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07392190

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.