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Overweight clinical trials recruiting in the U.S.

204 studies for Overweight are recruiting participants at sites across the United States.

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Recently updated studies

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07668414

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07595549

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07794579

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07720271

Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)

RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 60 ยท Women ยท Updated Sep 28, 2026 ยท NCT03407079

Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D

RecruitingPhase 1
Ages 18 to 65 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07399678

Physical and Behavioral Traits of Overweight and Obese Adults

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT00428987

Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss

RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07837973

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07752979

Safety and Drug Concentrations of REGN20934 in Adults With Overweight or Obesity

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07594093

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

RecruitingPhase 3
Ages 6 to 17 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06672549

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06937099

A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or Obesity

RecruitingPhase 1
Ages 18 to 70 ยท All sexes ยท Updated Sep 23, 2026 ยท NCT07803744

FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)

Recruiting
Ages 18 to 75 ยท All sexes ยท Updated Sep 23, 2026 ยท NCT06724406

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07321886

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07784270

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07282600

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07369011

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07392190

CHOICE to AVOID or RESIST

RecruitingHealthy volunteers welcome
Ages 18 to 80 ยท All sexes ยท Updated Sep 22, 2026 ยท NCT06521021

Impact of Lean Pork on Endothelial Function in Perimenopause

RecruitingHealthy volunteers welcome
Ages 40 to 55 ยท Women ยท Updated Sep 22, 2026 ยท NCT06976112

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.