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Prostate Assessment with Restriction Spectrum Imaging (RSI) MRI

RecruitingObservational study

Quantitative Diffusion MRI for Prostate Cancer Detection and Monitoring

Who can join

Ages 18 and older · Men

Full eligibility criteria
Inclusion Criteria:

* Male, aged ≥18 years, with histologically confirmed adenocarcinoma of the prostate
* Has already undergone prostate MRI and/or scheduled to undergo clinically indicated radical prostatectomy (to permit whole-mount histopathology correlation).
* Intended treatment and follow-up according to standard of care for prostate cancer
* In good general health as evidenced by medical history and ECOG performance status 0-2
* Provision of signed and dated informed consent form
* Stated willingness to comply with all study procedures and availability for the duration of the study

Exclusion Criteria:

* Prior treatment for prostate cancer (cryotherapy, high frequency focused ultrasound, prostatectomy)
* Hip prosthesis
* Contraindication to MRI, per institutional requirements
* Patient has a history or current evidence of any condition, therapy, or laboratory abnormality that might confound the results of the trial, interfere with the subject's participation for the full duration of the trial, or is not in the best interest of the subject to participate, in the opinion of the treating investigator.

About the study

This single-center study will enroll 40 male participants to complete 2 diffusion magnetic resonance images within 30 days of each other.

What is being tested

Sponsor: University of California, San Diego · Participants: 100 · Started: Nov 2, 2021

Contact the study team

Official record on ClinicalTrials.gov — NCT04992728

Locations in the U.S.

CaliforniaUCSD Moores Cancer Center, La Jolla

Conditions

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.