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Understanding Motivation in Parkinson's Patients Through Neurophysiology

Recruiting

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Has Parkinson's Disease or Dystonia
* Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN
* Has DBS device implanted either bilaterally or unilaterally
* Male or female
* More than 1 month post-DBS surgery

Exclusion Criteria:

* Severe cognitive impairments
* Has MOCA score below 20
* Pregnancy
* Age less than 18 years old

About the study

The study aims to better understand motivation and value-based decision-making in Parkinson's patients through neurophysiology using Medtronic's Percept DBS device. By combining behavioral tasks with neural recordings, the study seeks to uncover how DBS affects motivation, particularly in relation to effort, reward, and timing.

What is being tested

Sponsor: University of California, San Francisco · Participants: 70 · Started: Oct 30, 2021

Contact the study team

Official record on ClinicalTrials.gov — NCT05065151

Locations in the U.S.

CaliforniaUniversity of California San Francisco, San Francisco

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.