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Parkinson's Disease clinical trials recruiting in the U.S.

211 studies for Parkinson's Disease are recruiting participants at sites across the United States.

Parkinson's disease (PD) is a movement disorder. It causes tremors, stiffness, and slow movement. It gets worse over time. Learn what can help.

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Recently updated studies

Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments

RecruitingPhase 1/2
Ages 45 and older · All sexes · Updated Nov 13, 2026 · NCT07154511

Neocortical Microarchitecture of Executive Function

Recruiting
Ages 45 to 85 · All sexes · Updated Nov 13, 2026 · NCT06778135

A Trial Investigating Lu AF28996 in Adults With Parkinson's Disease Who Have Motor Fluctuations

RecruitingPhase 2
Ages 40 to 85 · All sexes · Updated Nov 13, 2026 · NCT07514858

Adaptango Performance PRocess for Older Adults Community reHabilitation

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07824128

Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control

Recruiting
Ages 18 to 75 · All sexes · Updated Nov 12, 2026 · NCT07056361

SAD Study in Patients With Parkinson's Disease and Motor Fluctuations

RecruitingPhase 1
Ages 40 to 80 · All sexes · Updated Nov 12, 2026 · NCT07422675

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT02071134

Deep Brain Stimulation Therapy in Movement Disorders

Recruiting
Ages 18 to 100 · All sexes · Updated Nov 12, 2026 · NCT02119611

Deep Brain Stimulation Surgery for Movement Disorders

Recruiting
Ages 18 to 99 · All sexes · Updated Nov 12, 2026 · NCT01581580

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

RecruitingObservational study
All ages · All sexes · Updated Nov 12, 2026 · NCT03664609

Evaluation and Treatment of Neurosurgical Disorders

RecruitingObservational study
Ages 4 to 99 · All sexes · Updated Nov 10, 2026 · NCT00060541

Study to Test Effects and Safety of RO7568282 in Early Parkinson's Disease

RecruitingPhase 2
Ages 40 to 85 · All sexes · Updated Nov 9, 2026 · NCT07781644

Striatal and Extra-Striatal Cholinergic Terminal Density in LRRK2-PD Mutation

RecruitingObservational study
Ages 45 and older · All sexes · Updated Nov 6, 2026 · NCT07642908

Accelerated rTMS for Apathy in Parkinson's Disease

Recruiting
Ages 45 to 85 · All sexes · Updated Nov 5, 2026 · NCT07399496

Tributyrin for Progressive Supranuclear Palsy (PSP): Virtual Trial

RecruitingPhase 1/2
Ages 45 and older · All sexes · Updated Nov 5, 2026 · NCT07863180

Parkinson's Disease in Type 1 Gaucher Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Nov 5, 2026 · NCT07886879

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Nov 2, 2026 · NCT04396873

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

RecruitingPhase 3
Ages 45 to 75 · All sexes · Updated Nov 2, 2026 · NCT06944522

A Study of Buntanetap in Participants With PD

RecruitingPhase 2/3
Ages 40 to 85 · All sexes · Updated Oct 30, 2026 · NCT07284784

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.