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Parkinson's Disease clinical trials recruiting in the U.S.
210 studies for Parkinson's Disease are recruiting participants at sites across the United States.
Parkinson's disease (PD) is a movement disorder. It causes tremors, stiffness, and slow movement. It gets worse over time. Learn what can help.
Cities with the most studies
- New York City, NY23 studies
- Boston, MA20 studies
- Cleveland, OH18 studies
- Minneapolis, MN17 studies
- Nashville, TN16 studies
- San Francisco, CA15 studies
- Philadelphia, PA15 studies
- Farmington Hills, MI14 studies
- Miami, FL14 studies
- New Haven, CT14 studies
- Chicago, IL14 studies
- Gainesville, FL13 studies
- Charleston, SC13 studies
- Tampa, FL12 studies
- Atlanta, GA12 studies
- Aurora, CO12 studies
- Portland, OR12 studies
- Orlando, FL11 studies
- Washington, DC11 studies
- Birmingham, AL11 studies
- Round Rock, TX10 studies
- Ann Arbor, MI10 studies
- Durham, NC10 studies
- Los Angeles, CA10 studies
- Houston, TX10 studies
- Kirkland, WA9 studies
- Dallas, TX9 studies
- Baltimore, MD9 studies
- Kansas City, KS9 studies
- Mountain View, CA9 studies
- Boca Raton, FL9 studies
- St. Louis, MO9 studies
- Las Vegas, NV8 studies
- Spokane, WA7 studies
- Phoenix, AZ7 studies
- San Diego, CA6 studies
- Lexington, KY6 studies
- Columbus, OH6 studies
- Denver, CO6 studies
- Seattle, WA6 studies
By state
- Alabama12 studies
- Arizona13 studies
- Arkansas5 studies
- California37 studies
- Colorado18 studies
- Connecticut19 studies
- Delaware3 studies
- District of Columbia5 studies
- Florida35 studies
- Georgia13 studies
- Illinois19 studies
- Indiana5 studies
- Iowa4 studies
- Kansas11 studies
- Kentucky9 studies
- Louisiana3 studies
- Maryland15 studies
- Massachusetts21 studies
- Michigan22 studies
- Minnesota19 studies
- Missouri10 studies
- Nevada8 studies
- New Jersey3 studies
- New Mexico5 studies
- New York31 studies
- North Carolina15 studies
- Ohio25 studies
- Oklahoma4 studies
- Oregon12 studies
- Pennsylvania19 studies
- South Carolina13 studies
- Tennessee19 studies
- Texas27 studies
- Utah6 studies
- Vermont4 studies
- Virginia11 studies
- Washington16 studies
- Wisconsin4 studies
Recently updated studies
Deep Brain Stimulation Therapy in Movement Disorders
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 28, 2026 · NCT02119611Evaluation and Treatment of Neurosurgical Disorders
RecruitingObservational study
Ages 4 to 99 · All sexes · Updated Sep 28, 2026 · NCT00060541The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease
RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Sep 28, 2026 · NCT07610369A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
RecruitingPhase 2/3
Ages 40 to 80 · All sexes · Updated Sep 28, 2026 · NCT06976268Bayesian Optimization of DBS for Gait
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07835308GBPDC: Gut-Brain in PD Consortium Master Protocol
RecruitingObservational studyHealthy volunteers welcome
Ages 21 to 80 · All sexes · Updated Sep 25, 2026 · NCT07567794Speech Learning and Speech Production in Parkinson's Disease
Recruiting
Ages 45 and older · All sexes · Updated Sep 22, 2026 · NCT07403539Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease
RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Sep 21, 2026 · NCT07005180A Study of Buntanetap in Participants With PD
RecruitingPhase 2/3
Ages 40 to 85 · All sexes · Updated Sep 21, 2026 · NCT07284784This Protocol is a Sub-study Under the PPMI Program. It is a Longitudinal, Single-center Study to Assess the Performance of [18F]AV-133 Imaging Using High and Standard Resolution PET in Individuals Enrolled With Parkinson's Disease (PD) for up to 12 Months.
RecruitingPhase 2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07830654Natural History Protocol for Movement Disorders
RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 100 · All sexes · Updated Sep 18, 2026 · NCT05413291Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control
Recruiting
Ages 18 to 75 · All sexes · Updated Sep 18, 2026 · NCT07056361RESvEraTrol in Parkinson's Disease (RESET)
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 18, 2026 · NCT07592767PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Sep 18, 2026 · NCT04396873Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT02071134Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT01734122Treatment of Cognitive and Sensorimotor Deficits in Parkinson's Disease With High Definition Transcranial Direct Current Stimulation
Recruiting
Ages 50 to 90 · All sexes · Updated Sep 16, 2026 · NCT07534397Dual Frequency Stimulation in Parkinson's Disease
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04650932Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07398157Automated Daytime Adaptive Deep Brain Stimulation Parameter Optimization in Patients Implanted With Percept Neurostimulator
Recruiting
Ages 25 to 75 · All sexes · Updated Sep 14, 2026 · NCT07682311A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 11, 2026 · NCT07804615Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease
RecruitingPhase 2
Ages 50 to 90 · All sexes · Updated Sep 11, 2026 · NCT06638944A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
RecruitingPhase 2
Ages 30 to 80 · All sexes · Updated Sep 10, 2026 · NCT07432958Parkinson's Foundation PD GENEration Genetic Registry
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04994015Parkinson Progression Marker Initiative Online (PPMI Online)
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05065060From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.