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Parkinson's Disease clinical trials recruiting in the U.S.

210 studies for Parkinson's Disease are recruiting participants at sites across the United States.

Parkinson's disease (PD) is a movement disorder. It causes tremors, stiffness, and slow movement. It gets worse over time. Learn what can help.

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Recently updated studies

Deep Brain Stimulation Therapy in Movement Disorders

Recruiting
Ages 18 to 100 · All sexes · Updated Sep 28, 2026 · NCT02119611

Evaluation and Treatment of Neurosurgical Disorders

RecruitingObservational study
Ages 4 to 99 · All sexes · Updated Sep 28, 2026 · NCT00060541

The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease

RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Sep 28, 2026 · NCT07610369

Bayesian Optimization of DBS for Gait

RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07835308

GBPDC: Gut-Brain in PD Consortium Master Protocol

RecruitingObservational studyHealthy volunteers welcome
Ages 21 to 80 · All sexes · Updated Sep 25, 2026 · NCT07567794

Speech Learning and Speech Production in Parkinson's Disease

Recruiting
Ages 45 and older · All sexes · Updated Sep 22, 2026 · NCT07403539

Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease

RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Sep 21, 2026 · NCT07005180

A Study of Buntanetap in Participants With PD

RecruitingPhase 2/3
Ages 40 to 85 · All sexes · Updated Sep 21, 2026 · NCT07284784

Natural History Protocol for Movement Disorders

RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 100 · All sexes · Updated Sep 18, 2026 · NCT05413291

Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control

Recruiting
Ages 18 to 75 · All sexes · Updated Sep 18, 2026 · NCT07056361

RESvEraTrol in Parkinson's Disease (RESET)

RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 18, 2026 · NCT07592767

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Sep 18, 2026 · NCT04396873

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT02071134

Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT01734122

Dual Frequency Stimulation in Parkinson's Disease

Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04650932

Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease

Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07398157

Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease

RecruitingPhase 2
Ages 50 to 90 · All sexes · Updated Sep 11, 2026 · NCT06638944

Parkinson's Foundation PD GENEration Genetic Registry

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04994015

Parkinson Progression Marker Initiative Online (PPMI Online)

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05065060

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.