Home › Tetralogy of Fallot › NCT05122962

Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart Diseases

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Moderate (or greater) PR based on quantitative Doppler echocardiography.
* Repaired TOF
* Congenital Heart Disease diagnosis including but not limited to Ebstein's anomaly, coarctation of the aorta (COA), Fontan palliation, transposition of the great arteries, congenitally corrected transposition of the great arteries.

Exclusion Criteria:

* Pregnant Women
* Unable to undergo CMRI

About the study

This study is being done to determine the mechanism(s) contributing to the onset of symptoms (i.e. shortness of breath and/or palpitations) as well as changes in heart structure in patients with congenital heart disease (CHD)

What is being tested

• Remote Heart Rhythm Monitoring (diagnostic test)

Sponsor: Mayo Clinic · Participants: 300 · Started: Nov 1, 2021

Contact the study team

• Halley Davison · Phone: 507-422-6246

Official record on ClinicalTrials.gov — NCT05122962

Locations in the U.S.

Conditions

• Tetralogy of Fallot
• Congenital Heart Defects

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.