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HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease
Recruiting
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: 1. Adult patients ≥ 18 years old with diagnosis of cirrhosis based on histology, radiology, and/or elastography presenting to the emergency department or inpatient general medicine service 2. Patients must have one of the following: 1. Ascites (requiring diuretics or serial large volume paracenteses) 2. Hepatic hydrothorax (requiring diuretics) 3. Hepatic encephalopathy (requiring medications) Exclusion Criteria: All existing MGB home hospital criteria apply, with the following taking precedent for this specific condition 1. History of solid organ transplantation 2. On hemodialysis 3. MELD score \> 20 4. Score \<10 on Simplified Animal Naming Test (S-ANT1) 5. Current admission for hemodynamically significant GI bleeding or alcohol withdrawal 6. Require routine administration of controlled substances 7. Those deemed ineligible based on the MGH Home Hospital, inpatient medicine or hepatology clinician evaluation
About the study
This research study is evaluating a program that entails a healthcare at home intervention for people with advanced liver disease.
What is being tested
- Hepatology Home Hospital (behavioral)
Sponsor: Massachusetts General Hospital · Participants: 30 · Started: Jul 21, 2025
Contact the study team
- Nneka Ufere, MD, MSCE · Phone: 617-643-3408
Official record on ClinicalTrials.gov — NCT05205954
Locations in the U.S.
| Massachusetts | Massachusetts General Hospital, Boston Massachusetts General Hospital, Boston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.