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Dextromethorphan for Treatment of Postoperative Pain
Recruiting
A Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Perioperative Dextromethorphan Compared to Placebo for the Treatment of Postoperative Pain
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Main Inclusion Criteria: * Patients Age ≥18 planning to undergo total knee arthroplasty * ASA classes I - III Main Exclusion Criteria: * BMI ≥ 35 * History opioid abuse * History of intractable vomiting after previous surgery
About the study
A Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Perioperative Dextromethorphan compared to Placebo for the Treatment of Postoperative Pain
What is being tested
- Dextromethorphan Hydrobromide (drug)
- Placebo (drug)
Sponsor: Nathanael Heckmann · Participants: 160 · Started: Sep 15, 2022
Contact the study team
- Pui Yan, MS · Phone: 323-442-6984
Official record on ClinicalTrials.gov — NCT05278494
Locations in the U.S.
| California | Keck School of Medicine of USC, Los Angeles |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.