Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease

Participant:

Inclusion Criteria:

* confirmed HD mutation carriers and/or established family history alongside typical symptoms (i.e. chorea) of HD;
* early (stages 1 and 2) or moderate (stage 3) stages according to Shoulson-Fahn
* exhibit mild to moderate behavioral symptoms defined by severity scores in the PBA-S between 1 and 3 for any of the evaluated symptoms and no symptoms with a severity score of 4
* stable doses of medications for at least one month
* Have a caregiver willing to be present during tDCS sessions and answer questionnaires.

Exclusion Criteria:

* unstable medical conditions
* history of epilepsy
* metallic objects in the brain
* Have a caregiver willing to be present during tDCS sessions and answer questionnaires.
* clinical diagnosis of major cognitive disorder or dementia
* Have risk of suicidal behavior, defined as any suicidal behavior or suicidal ideation of type 4 or type 5 based on the Columbia-Suicide Severity Rating Scale (C-SSRS) in the 3 months prior to screening
* simultaneous participation in other clinical trial
* Individuals determined to be incapable of consent per past medical history or via assessment by the study staff at time of consent.

Caregiver:

Inclusion Criteria:

-willingness to participate in the study

Exclusion Criteria:

-motor/cognitive symptoms related to Alzheimer's disease or Huntington's disease that might impair the ability to assist the participant during the research study.