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Huntington's Disease clinical trials recruiting in the U.S.
18 studies for Huntington's Disease are recruiting participants at sites across the United States.
Huntington's disease (HD) is an inherited disease that causes nerve cells in the brain to waste away. It causes disability that gets worse over time.
Cities with the most studies
- Houston, TX5 studies
- Durham, NC4 studies
- Denver, CO4 studies
- Baltimore, MD4 studies
- Washington, DC4 studies
- Nashville, TN4 studies
- Columbus, OH4 studies
- Boston, MA4 studies
- New York City, NY4 studies
- Rochester, NY4 studies
- Orlando, FL3 studies
- San Diego, CA3 studies
- Wichita, KS3 studies
- Cincinnati, OH3 studies
- Sacramento, CA3 studies
- Seattle, WA3 studies
- Chicago, IL3 studies
- Portland, OR3 studies
- Burlington, VT3 studies
- Birmingham, AL3 studies
- Cleveland, OH3 studies
- Philadelphia, PA3 studies
- Pittsburgh, PA3 studies
By state
- Alabama3 studies
- California5 studies
- Colorado4 studies
- District of Columbia4 studies
- Florida6 studies
- Illinois3 studies
- Kansas3 studies
- Maryland4 studies
- Massachusetts4 studies
- New York6 studies
- North Carolina4 studies
- Ohio5 studies
- Oregon3 studies
- Pennsylvania3 studies
- Tennessee4 studies
- Texas6 studies
- Vermont3 studies
- Washington3 studies
Recently updated studies
Pridopidine Phase 3 Study in Huntington's Disease
RecruitingPhase 3
Ages 23 to 65 · All sexes · Updated Sep 24, 2026 · NCT07609108A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease
RecruitingPhase 3
Ages 21 to 70 · All sexes · Updated Sep 22, 2026 · NCT07326709Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease
RecruitingPhase 2/3
Ages 25 and older · All sexes · Updated Sep 21, 2026 · NCT07378644Digital Measures for Clinical Trial Endpoints in Huntington's Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 25 to 65 · All sexes · Updated Aug 17, 2026 · NCT07010705A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease
RecruitingPhase 1/2
Ages 25 to 65 · All sexes · Updated May 5, 2026 · NCT06826612HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 11 to 75 · All sexes · Updated Apr 27, 2026 · NCT02855476Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease
RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Apr 13, 2026 · NCT07451613Cognitive Assessment Tools for Huntington's Disease.
RecruitingObservational study
Ages 30 to 65 · All sexes · Updated Mar 2, 2026 · NCT06546488Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease
Recruiting
Ages 18 to 80 · All sexes · Updated Feb 11, 2026 · NCT05326451Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease
Recruiting
Ages 18 to 85 · All sexes · Updated Feb 11, 2026 · NCT06843252Retinal Imaging in Neurodegenerative Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 4, 2026 · NCT03233646Longitudinal Endpoint Assessment of Disease Burden in HD
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 10, 2025 · NCT06475898Gut Microbiomes in HD
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 18, 2025 · NCT06448546Huntington's Disease Biobank: Advancing Remote Monitoring and Deep Phenotyping
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Apr 24, 2025 · NCT06941662University of Central Florida CereBank
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · Women · Updated Mar 14, 2025 · NCT06876857NYSCF Scientific Discovery Biobank
RecruitingObservational study
30 Days · All sexes · Updated Mar 3, 2025 · NCT06203106Extracellular Vesicles for HD
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Dec 6, 2024 · NCT06082713Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 28, 2024 · NCT01574053From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.