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The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

Recovery of Ventilation After General Anesthesia for Robotic-Assisted Laparoscopic Nephrectomy or Prostatectomy: The Effect of Oxygen Supplementation

Who can join

Ages 18 to 70 · All sexes

Inclusion Criteria:

* American Society of Anesthesiologists (ASA) physical status I-III
* Body mass index (BMI) less than 40 kg/m2
* Scheduled to undergo robotic-assisted radical laparoscopic nephrectomy or prostatectomy.

Exclusion Criteria:

* Patients with a diagnosis of chronic obstructive pulmonary disorder (COPD), severe neurological, cardiopulmonary, psychiatric, or untreated thyroid disorder
* Chronic pain condition that is being treated with opioids
* Patients with a hematocrit lower than 30% at the end of surgery, or those with an excessive blood loss, requiring transfusion of blood products during surgery.

About the study

In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.

What is being tested

• Oxygen Gas for Inhalation (other)

Sponsor: Stanford University · Participants: 60 · Started: Oct 4, 2022

Contact the study team

• Anthony Doufas, MD, PhD · Phone: 650-498-7699

Official record on ClinicalTrials.gov — NCT05379673

Locations in the U.S.

Conditions

• Respiratory Failure

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.