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Respiratory Failure clinical trials recruiting in the U.S.
28 studies for Respiratory Failure are recruiting participants at sites across the United States.
Respiratory failure happens when not enough oxygen passes from your lungs to your blood. Lung diseases can cause respiratory failure. Read more.
Cities with the most studies
- New York City, NY7 studies
- Philadelphia, PA5 studies
- Los Angeles, CA4 studies
- Houston, TX4 studies
- Rochester, NY3 studies
- Chicago, IL3 studies
- Rochester, MN3 studies
- Pittsburgh, PA3 studies
- San Francisco, CA3 studies
- Baltimore, MD3 studies
By state
- California9 studies
- Florida3 studies
- Illinois3 studies
- Maryland3 studies
- Minnesota4 studies
- New York11 studies
- Pennsylvania7 studies
- Texas4 studies
Recently updated studies
Developing New Ways to Detect Respiratory Impairment Early in ALS
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07844590The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia
Recruiting
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT05379673Phase Resolved Functional Lung MRI and Oscillometry for the Observation of Healthy Lung Function
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07614685Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT05947955Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children
RecruitingObservational study
1 Day – 17 Years · All sexes · Updated Aug 27, 2026 · NCT07613918Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)
RecruitingPhase 4
28 Days · All sexes · Updated Aug 18, 2026 · NCT07322133COMPARE-VENT Feasibility Pilot Study
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07656259Multicenter HomeVENT: Home Values and Experiences Navigation Track
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT06102330Supraglottic Airway for Resuscitation in Preemies
Recruiting
0 Days – 1 Day · All sexes · Updated Jul 14, 2026 · NCT07419438Thoracoabdominal Asynchrony and Respiratory Distress
Recruiting
28 Days – 17 Years · All sexes · Updated Jul 13, 2026 · NCT04626154Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT06066502A Clinical Trial to Evaluate agenT-797 Plus Standard of Care in Participants With Severe Pneumonia With Moderate to Severe Acute Hypoxemic Respiratory Failure
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT07615010A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT07071935Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT06341972Cardiopulmonary Exercise Testing and Oscillometry for the Evaluation of Dyspnea
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06554353A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure
Recruiting
Ages 18 and older · All sexes · Updated May 28, 2026 · NCT06671015Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy
RecruitingObservational studyHealthy volunteers welcome
Ages 3 to 17 · All sexes · Updated May 8, 2026 · NCT07573150Platform of Randomized Adaptive Clinical Trials in Critical Illness
Recruiting
Ages 18 and older · All sexes · Updated May 7, 2026 · NCT05440851Body Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT07356310Low and High Flow Suctioning in Intubated Infants
Recruiting
28 Days · All sexes · Updated Apr 13, 2026 · NCT06443970Combined Respiratory Training in Persons With ALS
Recruiting
Ages 18 to 90 · All sexes · Updated Dec 23, 2025 · NCT05913882Hospital Airway Resuscitation Trial
Recruiting
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05520762Analgesia-First Sedation in Trauma Patients
Recruiting
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05751863The Family Perspectives Project Pilot Trial
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 15, 2025 · NCT06039501The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICU
Recruiting
Ages 18 and older · All sexes · Updated Apr 9, 2025 · NCT03642002From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.