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Respiratory Failure clinical trials recruiting in the U.S.

28 studies for Respiratory Failure are recruiting participants at sites across the United States.

Respiratory failure happens when not enough oxygen passes from your lungs to your blood. Lung diseases can cause respiratory failure. Read more.

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Recently updated studies

Developing New Ways to Detect Respiratory Impairment Early in ALS

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07844590

The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

Recruiting
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT05379673

Phase Resolved Functional Lung MRI and Oscillometry for the Observation of Healthy Lung Function

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07614685

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT05947955

Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children

RecruitingObservational study
1 Day – 17 Years · All sexes · Updated Aug 27, 2026 · NCT07613918

Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)

RecruitingPhase 4
28 Days · All sexes · Updated Aug 18, 2026 · NCT07322133

COMPARE-VENT Feasibility Pilot Study

Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07656259

Multicenter HomeVENT: Home Values and Experiences Navigation Track

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT06102330

Supraglottic Airway for Resuscitation in Preemies

Recruiting
0 Days – 1 Day · All sexes · Updated Jul 14, 2026 · NCT07419438

Thoracoabdominal Asynchrony and Respiratory Distress

Recruiting
28 Days – 17 Years · All sexes · Updated Jul 13, 2026 · NCT04626154

Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT06066502

A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT07071935

Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT06341972

Cardiopulmonary Exercise Testing and Oscillometry for the Evaluation of Dyspnea

RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06554353

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

RecruitingObservational studyHealthy volunteers welcome
Ages 3 to 17 · All sexes · Updated May 8, 2026 · NCT07573150

Platform of Randomized Adaptive Clinical Trials in Critical Illness

Recruiting
Ages 18 and older · All sexes · Updated May 7, 2026 · NCT05440851

Body Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry

RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT07356310

Low and High Flow Suctioning in Intubated Infants

Recruiting
28 Days · All sexes · Updated Apr 13, 2026 · NCT06443970

Combined Respiratory Training in Persons With ALS

Recruiting
Ages 18 to 90 · All sexes · Updated Dec 23, 2025 · NCT05913882

Hospital Airway Resuscitation Trial

Recruiting
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05520762

Analgesia-First Sedation in Trauma Patients

Recruiting
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05751863

The Family Perspectives Project Pilot Trial

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 15, 2025 · NCT06039501

The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICU

Recruiting
Ages 18 and older · All sexes · Updated Apr 9, 2025 · NCT03642002

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.