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CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth
Social Cognitive Training to Enhance the Efficacy of CBT forDepression in Youth: A Developmental Approach (R33)
Who can join
Ages 13 to 17 · All sexes
Full eligibility criteria
Inclusion Criteria: 1. Participants ages 13- through 17-years-old 2. Youth must have a diagnosis of a current depressive disorder (e.g., major depressive episode; persistent depressive disorder) or a score on the Patient Health Questionnaire (PHQ9) \> 15 Exclusion Criteria: * ever met criteria for a diagnosis of bipolar disorder, schizophrenia, autism, or conduct disorder * current alcohol or substance use disorder with significant impairment * imminent risk of suicide * reading level \< 4th grade
About the study
Depression in youth is a serious public health concern for which more personalized treatments are needed. This randomized controlled trial will test the effect of an intervention aimed at enhancing social cognitive capacities (e.g., ability to take another's perspective), thereby making treatment of depression in youth more efficient and effective. Participants in the R33 (N=82) will be youth between ages 13- through 17-years-old currently experiencing depression. Youth will be randomized to either an enhanced CBT intervention that teaches social cognitive skills, particularly social perspective taking and theory of mind (CBTSCT) as compared to CBT only. The primary target is improvement in both social cognitive skills and depressive symptoms at post-treatment and at a 6-month follow-up.
What is being tested
- Cognitive behavioral therapy plus social cognitive training (CBTSCT) (behavioral)
Sponsor: Vanderbilt University · Participants: 82 · Started: Oct 10, 2022
Contact the study team
- Judy Garber, PhD · Phone: 615-330-5605
- Steven D Hollon, PhD · Phone: 615-373-2422
Official record on ClinicalTrials.gov — NCT05456035
Locations in the U.S.
| Tennessee | Judy Garber, Nashville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.