Home › Drug Resistant Epilepsy › NCT05493722
Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * medically refractory epilepsy * already have a deep brain stimulator in place Exclusion Criteria: * severe dementia at investigator discretion
About the study
Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization based on power spectral density (PSD) measures.
What is being tested
- Physician-Selected Settings Stimulation (other)
- Optimized Settings Stimulation (other)
- DBS Setting Optimization (other)
Sponsor: University of Minnesota · Participants: 30 · Started: Jul 1, 2021
Contact the study team
- Anusha Duggirala · Phone: 612-624-3672
Official record on ClinicalTrials.gov — NCT05493722
Locations in the U.S.
| Minnesota | University of Minnesota, Minneapolis |
Conditions
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.