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Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

RecruitingEarly phase 1

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* medically refractory epilepsy
* already have a deep brain stimulator in place

Exclusion Criteria:

* severe dementia at investigator discretion

About the study

Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization based on power spectral density (PSD) measures.

What is being tested

Sponsor: University of Minnesota · Participants: 20 · Started: Sep 15, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT05493722

Locations in the U.S.

MinnesotaUniversity of Minnesota, Minneapolis

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.