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Post-ablation Alcohol Impacts Arrhythmia Recurrence, Quality of Life and Cognition in AF
Impact of Post-ablation Alcohol Intake on Arrhythmia Recurrence, Quality of Life and Cognition in Patients With Atrial Fibrillation
Who can join
Ages 18 to 85 · All sexes
Full eligibility criteria
Inclusion Criteria: * AF patients that regularly consume \>5 alcoholic drink (\*12 g of pure alcohol/drink)/week * Paroxysmal or persistent AF * First catheter ablation History of alcohol-induced arrhythmia * Willing to sign the written informed consent Exclusion Criteria: * Binge drinkers (alcohol dependence) * Non-drinkers * LVEF \<35% * Psychiatric conditions * MoCA score ≤ 17 on Montreal Cognitive Assessment (MoCA) * Patients with established dementia * Medically unstable patients (acute/unstable or poorly controlled problems that would demand focused, relatively urgent or emergent medical attention) * Unwilling for alcohol-abstinence * Long-standing persistence AF * Patient under legal protection * Pregnancy
About the study
Earlier studies have shown a dose-dependent relationship between alcohol intake and incident atrial fibrillation (AF) as well as a causal link with several risk factors for AF such as hypertension, obesity and sleep apnea. However, the effect of drinking (alcohol) on post-ablation outcome such as arrhythmia recurrence, quality of life (QoL) and cognitive function in AF patients is unclear. Therefore, we aim to find the answer for a very frequently asked question, "is it safe to continue drinking alcohol (at the pre-ablation level) following catheter ablation OR should the intake be reduced for better outcome?", in this randomized trial.
What is being tested
- Study arm (behavioral)
Sponsor: Texas Cardiac Arrhythmia Research Foundation · Participants: 184 · Started: Aug 22, 2022
Contact the study team
- Andrea Natale · Phone: 5125448186
- Sanghamitra Mohanty · Phone: 5127842651
Official record on ClinicalTrials.gov — NCT05510167
Locations in the U.S.
| Texas | Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.