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Hospital Airway Resuscitation Trial

Hospital Airway Resuscitation Trial: A Cluster-Randomized, Pragmatic Trial

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

1. Adult aged \>=18 years
2. Admitted to the hospital for any condition
3. Suffered in-hospital cardiac arrest (loss of pulse and ≥2 minutes of chest compressions)
4. Need for assisted ventilation (defined by initiation of bag-mask-ventilation or other supported ventilation)

Exclusion Criteria:

1. Cardiac arrest in the Operating Room or other area not responded to by Critical Care/Emergency Department (ED) teams.
2. Cardiac arrest in which an invasive airway (i.e. endotracheal tube, tracheostomy tube) is already in place
3. Patients with Do Not Resuscitate or Do Not Intubate orders

About the study

The Hospital Airway Resuscitation Trial (HART) is a cluster-randomized, pragmatic trial of advanced airway management with a strategy of first choice supraglottic airway vs. first choice endotracheal intubation during in-hospital cardiac arrest.

What is being tested

• A strategy of first choice supraglottic airway (procedure)
• A strategy of first choice endotracheal intubation (procedure)

Sponsor: Montefiore Medical Center · Participants: 1,060 · Started: Feb 10, 2023

Contact the study team

• Ari Moskowitz, MD · Phone: 718-920-5440

Official record on ClinicalTrials.gov — NCT05520762

Locations in the U.S.

Conditions

• Sudden Cardiac Arrest
• Respiratory Failure

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.