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Acupuncture Therapy and Hypertension

Recruiting

Neuroimmune Mechanisms Underlying Electroacupuncture Effect on Vascular Function

Who can join

Ages 45 to 75 · All sexes

Full eligibility criteria
Inclusion Criteria:

1. Subjects from 45 to 75 years of age
2. Clinically diagnosed with mild to moderate hypertension and ON or OFF medication (Office SBP \> 140 mmHg and \< 160 mmHg Or ABPM average SBP \> 130 mmHg and \< 145 mmHg), and
3. No significant ECG change reflecting ischemia (i.e. ST elevation or depression) at rest will be recruited to participate in this study.

Exclusion Criteria:

1. Subjects will be excluded if pregnant or nursing.
2. Subjects will be excluded if they have coronary disease (by history or on ECG screening), conduction abnormalities on ECG consistent with left bundle branch block, cardiac arrhythmias associated with low blood pressure (\<90 mmHg), peripheral vascular disease, orthopedic disease, diabetic neuropathy or severe hypertension (BP \>170 mmHg systolic or \>110 mmHg diastolic), or any other physical or psychological illness.
3. Those with known sensitivity to any topical preparations or strong reactions to medical dressings and skin tapes also will be excluded.
4. Inability our or unwillingness of individual to give written informed consent.

About the study

Acupuncture therapy will be provided to reduce blood pressure in hypertensive patients. The mild to moderate hypertensive patients will be either on or off hypertensive medications. The course last for 8 weeks and the frequency is once a week.

What is being tested

Sponsor: University of California, Irvine · Participants: 72 · Started: Jan 1, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT05530512

Locations in the U.S.

CaliforniaSusan Samueli Integrative Health Institute, Irvine
University of California, Irvine, Health Sciences Medical Center, Orange

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.