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Postpartum Intervention for Mothers With Opioid Use Disorders

Postpartum Intervention for Mothers With Opioid Use Disorders - Brain-Behavior Mechanisms

Who can join

Ages 18 to 50 · Women · Healthy volunteers welcome

Inclusion Criteria:

* mothers aged 18-50 from SBU or UM with diagnosis of Opioid Use Disorder (OUD); and/or receiving medication assisted treatment (such as buprenorphine or methadone)
* with a child aged 5 or less
* able to read, hear and understand English adequately enough to provide informed consent

Exclusion Criteria:

1. require immediate clinical care for suicidal/homicidal risk or psychosis (please see Protection of Human Subjects section for clinical management of suicidal risk);
2. For magnetic resonance imaging (MRI) of the brain, potential participants will be excluded if they:

1\) have ferromagnetic metal in their heads 2) have severe claustrophobia that prevents participation in the neuroimaging 3) have serious neurological condition that could interfere with neuroimaging, including a brain tumor, multiple sclerosis or significant head trauma 4) Exclusion from MRI does not necessarily exclude participant from study.

About the study

Opioid use disorder (OUD) is a fast-growing and devastating epidemic in the US with many mothers suffering cravings, depression, impaired interpersonal interactions and maladaptive parenting behaviors that may lead to child maltreatment and costly utilization of foster care. This interdisciplinary multisite project will begin with the high risk R61 phase, in which the investigators will administer the parenting intervention "Mom Power" to mothers with OUD during the first 6 months postpartum and look for effects on drug use, mood and brain mechanisms; and, If validated, the investigators will continue in the R33 with more brain mechanism investigation and outcome studies a larger sample. The completion of this grant will clarify the effects of parenting intervention for mothers with OUD, and yield brain-based biomarkers that may be connected with inexpensive measures toward improved treatment of families suffering OUD, their children and society - which ultimately bears much of the cost for the common trans-generational problems of peripartum drug use.

What is being tested

• Mom Power (behavioral)

Sponsor: Stony Brook University · Participants: 50 · Started: Feb 14, 2023

Contact the study team

• Elle Eggers, BSc · Phone: 636-667-0135
• Diana Saum, MA, MSW · Phone: 3016334402

Official record on ClinicalTrials.gov — NCT05614661

Locations in the U.S.

Conditions

• Opioid Overdose

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.