Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure

Inclusion Criteria:

Heart failure patients regardless of ejection fraction (HFpEF or HFrEF) with one or more of the following:

* NYHA Class III HF
* NYHA Class IV HF

OR

* NYHA Class II HF with one or more of the following:
* Chronic Kidney Disease (eGFR\<60 within the past 6 months)
* HF hospitalization (defined as HF listed as the major reason for hospitalization) within 9 months prior to screening visit and NT-proBNP \> 200 pg/ml\* for patients not in AF or \> 600 pg/ml\* for patients in AF on screening ECG+
* NT-proBNP \> 300 pg/ml\* for patients not in AF or \> 900 pg/ml\* for patients in AF on the screening visit ECG+
* Chronic obstructive pulmonary disease (COPD)

Exclusion Criteria:

* Under 18 years of age

  * Patients with severe COPD (GOLD stage III or IV)
  * Limited mobility preventing application of device or no caregiver to assist
  * Cognitive impairments that would limit the application and proper use of the device
  * Skin allergies or skin sensitivities to silicone-based adhesives
  * Pregnancy (method of assessment at the discretion of the PI)
  * Not willing to shave chest hair if needed to apply device
  * Patients on chronic IV ionotropic therapy - (Milrinone, Dobutamine, and Dopamine)
  * Patients with any condition that might limit the survival to less than 1 year as assessed by the investigator
  * No cellular coverage (Patient's Home)\*\*
  * Skin breakdown on the left chest or breast area